In the present study, PCL (polycaprolactone) nanofibres were produced by the electrospinning method. The use of PCL electrospun biopolymer in biomedical applications has attracted considerable interest due to its chemical resistance, biodegradability, biocompatibility, and non-toxic characteristics. However, the hydrophobic nature of PCL polymer restricts the useage of PCL nanofibres for the cell adhesion and absorption. A hydrophilic and biocompatible PCL electrospun mat with a low water contact angle is an attractive strategy for development in tissue engineering and wound dressing. In this study, we demonstrate a feasible and simple method to produce hydrophilic PCL nanofibres for possible application in wound dressing. Chloroform/ethanol (EtOH) and chloroform/dimethylformamide (DMF) mixtures were used as two different solvent systems. The impact of the polymeric solution concentration, applied voltage, and solvent mixtures on the fibre surface morphology and water contact angle was investigated. Consequently, bead structures were observed at low concentrations but disappeared with increases in the concentration. It was observed that the size of beads decreased and the diameter of fibres increased with increasing voltage. The wettability of the webs changed from hydrophobic to hydrophilic with changes of the polymer concentration. The contact angle of the nanofibre mats decreased in both solvent systems as the concentration increased. The results showed that the lowest contact angle was obtained in 24% wt. PCL+chloroform/EtOH solution and was 68°. The highest contact angle was obtained in 4% wt. PCL+chloroform/EtOH solution and was 112°. Using this method, the surface hydrophilicity of the PCL nanofibres improved easily without any surface treatment.

Bioengineering Department Institute of Science and Technology Kahramanmaras Sutcu Imam University Avşar Mah BatıÇevreyolu Blv No 251 A 46040 Kahramanmaras Turkey

Department of Nanotechnology and Informatics Institute of Nanomaterials Advanced Technology and Innovation Technical University of Liberec Studentska 1402 2 46117 Liberec Czech Republic

Department of Nonwovens and Nanofibrous Materials Faculty of Textile Technical University of Liberec Studentska 1402 2 46117 Liberec Czech Republic

Textile Engineering Department Faculty of Engineering and Architecture Kahramanmaras Sutcu Imam University Avşar Mah BatıÇevreyolu Blv No 251 A 46040 Kahramanmaras Turkey

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