For decades, glucans have been studied for their biological and immunological activities. The scientific community has mainly focused on immune reactions, but other areas, such as cholesterol levels and diabetic retinopathy, have shown the positive effects of glucan supplementation. However, the majority of studies focused on possible cancer suppression, where glucans showed clear and significant effects on numerous types of cancers, leading not only to clinical trials, but to approval as an official drug. The aim of this review is to describe the current knowledge of this field.

Department of Immunology Institute of Microbiology Prague Czech Republic

Department of Pathology and Laboratory Medicine University of Louisville Louisville KY U S A

Institute of Public Health in Usti nad Labem Ústí nad Labem Czech Republic

References provided by Crossref.org

Trained Immunity as an Adaptive Branch of Innate Immunity