Genome-wide association studies have identified breast cancer risk variants in over 150 genomic regions, but the mechanisms underlying risk remain largely unknown. These regions were explored by combining association analysis with in silico genomic feature annotations. We defined 205 independent risk-associated signals with the set of credible causal variants in each one. In parallel, we used a Bayesian approach (PAINTOR) that combines genetic association, linkage disequilibrium and enriched genomic features to determine variants with high posterior probabilities of being causal. Potentially causal variants were significantly over-represented in active gene regulatory regions and transcription factor binding sites. We applied our INQUSIT pipeline for prioritizing genes as targets of those potentially causal variants, using gene expression (expression quantitative trait loci), chromatin interaction and functional annotations. Known cancer drivers, transcription factors and genes in the developmental, apoptosis, immune system and DNA integrity checkpoint gene ontology pathways were over-represented among the highest-confidence target genes.

Academic Unit of Pathology Department of Neuroscience University of Sheffield Sheffield UK

Anatomical Pathology The Alfred Hospital Melbourne Victoria Australia

Australian Breast Cancer Tissue Bank Westmead Institute for Medical Research University of Sydney Sydney New South Wales Australia

Axe Oncologie Centre de Recherche Centre Hospitalier Universitaire de Québec Université Laval Québec Québec Canada

Basser Center for BRCA Abramson Cancer Center University of Pennsylvania Philadelphia PA USA

Behavioral and Epidemiology Research Group American Cancer Society Atlanta GA USA

Biomedical Sciences Institute University of Porto Porto Portugal

Biostatistics and Computational Biology Branch National Institute of Environmental Health Sciences National Institutes of Health Research Triangle Park USA

BMC Faculty of Medicine University of Iceland Reykjavik Iceland

Breast Cancer Now Toby Robins Research Centre The Institute of Cancer Research London UK

Breast Cancer Research Programme Cancer Research Malaysia Kuala Lumpur Malaysia

Cancer and Environment Group Center for Research in Epidemiology and Population Health INSERM University Paris Sud University Paris Saclay Paris France

Cancer Center Kuopio University Hospital Kuopio Finland

Cancer Epidemiology Division Cancer Council Victoria Melbourne Victoria Australia

Cancer Epidemiology Group University Cancer Center Hamburg University Medical Center Hamburg Eppendorf Hamburg Germany

Cancer Genetics and Prevention Program University of California San Francisco San Francisco CA USA

Cáncer Hereditario Instituto de Biología y Genética Molecular Valladolid Spain

Cancer Prevention Program Fred Hutchinson Cancer Research Center Seattle WA USA

Cancer Research Institute Seoul National University Seoul Korea

Cancer Research UK Cambridge Institute Li Ka Shing Centre University of Cambridge Cambridge UK

Cancer Research UK Clinical Trials Unit Institute of Cancer Sciences University of Glasgow Glasgow UK

Cancer Risk and Prevention Clinic Dana Farber Cancer Institute Boston MA USA

Cancer Sciences Academic Unit Faculty of Medicine University of Southampton Southampton UK

Center for Clinical Cancer Genetics The University of Chicago Chicago IL USA

Center for Genomic Medicine at Rigshospitalet Copenhagen University Hospital Copenhagen Denmark

Center for Hereditary Breast and Ovarian Cancer Faculty of Medicine and University Hospital Cologne University of Cologne Cologne Germany

Center for Integrated Oncology Faculty of Medicine and University Hospital Cologne University of Cologne Cologne Germany

Center for Medical Genetics NorthShore University HealthSystem Evanston IL USA

Center for Population Health Research National Institute of Public Health Cuernavaca Mexico

Centre de Bioinformatique Biostatistique et Biologie Intégrative Institut Pasteur Paris France

Centre de Recherche du Centre Hospitalier de l'Université de Montréal Université de Montréal Montréal Québec Canada

Centre for Cancer Genetic Epidemiology Department of Oncology University of Cambridge Cambridge UK

Centre for Cancer Genetic Epidemiology Department of Public Health and Primary Care University of Cambridge Cambridge UK

Centre for Cancer Research and Cell Biology Queen's University Belfast Belfast UK

Centre for Epidemiology and Biostatistics Melbourne School of Population and Global Health The University of Melbourne Melbourne Victoria Australia

Centre for Medical Genetics Ghent University Ghent Belgium

Centro de Investigación en Biomédica en Red de Enfermedades Raras Madrid Spain

Channing Division of Network Medicine Department of Medicine Brigham and Women's Hospital and Harvard Medical School Boston MA USA

Chronic Disease Epidemiology Yale School of Public Health New Haven CT USA

Clalit National Israeli Cancer Control Center Carmel Medical Center and Technion Faculty of Medicine Haifa Israel

Clinical and Molecular Genetics Area Vall Hebron University Hospital Barcelona Spain

Clinical Cancer Genetics Program Division of Human Genetics Department of Internal Medicine The Comprehensive Cancer Center The Ohio State University Columbus OH USA

Clinical Cancer Genomics City of Hope Duarte CA USA

Clinical Cancer Research Center Aalborg University Hospital Aalborg Denmark

Clinical Genetics Branch Division of Cancer Epidemiology and Genetics National Cancer Institute National Institutes of Health Bethesda MD USA

Clinical Genetics Karolinska Institutet Stockholm Sweden

Clinical Genetics Research Laboratory Department of Cancer Biology and Genetics Memorial Sloan Kettering Cancer Center New York NY USA

Clinical Genetics Service Department of Medicine Memorial Sloan Kettering Cancer Center New York NY USA

Copenhagen General Population Study Herlev and Gentofte Hospital Copenhagen University Hospital Herlev Denmark

David Geffen School of Medicine Department of Medicine Division of Hematology and Oncology University of California Los Angeles Los Angeles CA USA

David Geffen School of Medicine Department of Obstetrics and Gynecology University of California Los Angeles Los Angeles CA USA

Département de Médecine Moléculaire Faculté de Médecine Centre de Recherche Centre Hospitalier Universitaire de Québec Laval University Québec City Québec Canada

Department of Biomedical Physiology and Kinesiology Simon Fraser University Burnaby British Columbia Canada

Department of Biomedical Sciences Seoul National University Graduate School Seoul Korea

Department of Breast Medical Oncology University of Texas MD Anderson Cancer Center Houston TX USA

Department of Breast Surgery Herlev and Gentofte Hospital Copenhagen University Hospital Herlev Denmark

Department of Cancer Biology and Genetics The Ohio State University Columbus OH USA

Department of Cancer Epidemiology and Genetics Masaryk Memorial Cancer Institute Brno Czech Republic

Department of Cancer Epidemiology Clinical Sciences Lund University Lund Sweden

Department of Cancer Genetics Institute for Cancer Research Oslo University Hospital Radiumhospitalet Oslo Norway

Department of Clinical Biochemistry Herlev and Gentofte Hospital Copenhagen University Hospital Herlev Denmark

Department of Clinical Genetics Erasmus University Medical Center Rotterdam the Netherlands

Department of Clinical Genetics Fox Chase Cancer Center Philadelphia PA USA

Department of Clinical Genetics Helsinki University Hospital University of Helsinki Helsinki Finland

Department of Clinical Genetics Karolinska University Hospital Stockholm Sweden

Department of Clinical Genetics Leiden University Medical Center Leiden the Netherlands

Department of Clinical Genetics Odense University Hospital Odence Denmark

Department of Clinical Medicine Aalborg University Aalborg Denmark

Department of Clinical Pathology The University of Melbourne Melbourne Victoria Australia

Department of Clinical Science and Education Södersjukhuset Karolinska Institutet Stockholm Sweden

Department of Dermatology Huntsman Cancer Institute University of Utah School of Medicine Salt Lake City UT USA

Department of Electron Microscopy Molecular Pathology and The Cyprus School of Molecular Medicine The Cyprus Institute of Neurology and Genetics Nicosia Cyprus

Department of Epidemiology Genetic Epidemiology Research Institute University of California Irvine Irvine CA USA

Department of Epidemiology Gillings School of Global Public Health and UNC Lineberger Comprehensive Cancer Center University of North Carolina at Chapel Hill Chapel Hill NC USA

Department of Epidemiology Harvard T H Chan School of Public Health Boston MA USA

Department of Epidemiology Mailman School of Public Health Columbia University New York NY USA

Department of Family Medicine and Public Health University of California San Diego La Jolla CA USA

Department of Genetics and Computational Biology QIMR Berghofer Medical Research Institute Brisbane Queensland Australia

Department of Genetics and Fundamental Medicine Bashkir State Medical University Ufa Russia

Department of Genetics and Pathology Pomeranian Medical University Szczecin Poland

Department of Genetics Portuguese Oncology Institute Porto Portugal

Department of Genetics University of Pretoria Pretoria South Africa

Department of Gynecology and Obstetrics Comprehensive Cancer Center ER EMN University Hospital Erlangen Friedrich Alexander University Erlangen Nuremberg Erlangen Germany

Department of Gynecology and Obstetrics University of Munich Munich Germany

Department of Health Science Research Division of Epidemiology Mayo Clinic Rochester MN USA

Department of Health Sciences Research Mayo Clinic Rochester MN USA

Department of Histopathology and Cytology Clinical Hospital 'Acibadem Sistina' Skopje Republic of North Macedonia

Department of Human Genetics Leiden University Medical Center Leiden the Netherlands

Department of Internal Medicine Division of Medical Oncology University of Kansas Medical Center Westwood KS USA

Department of Internal Medicine Evangelische Kliniken Bonn Johanniter Krankenhaus Bonn Germany

Department of Internal Medicine Huntsman Cancer Institute Salt Lake City UT USA

Department of Laboratory Medicine and Pathobiology University of Toronto Toronto Ontario Canada

Department of Laboratory Medicine and Pathology Mayo Clinic Rochester MN USA

Department of Medical Epidemiology and Biostatistics Karolinska Institutet Stockholm Sweden

Department of Medical Genetics University of Cambridge Cambridge UK

Department of Medical Oncology Beth Israel Deaconess Medical Center Boston MA USA

Department of Medical Oncology Family Cancer Clinic Erasmus MC Cancer Institute Rotterdam the Netherlands

Department of Medical Oncology University Hospital of Heraklion Heraklion Greece

Department of Medical Oncology Vall Hebron University Hospital Barcelona Spain

Department of Medicine Division of Hematology Oncology UPMC Hillman Cancer Center University of Pittsburgh School of Medicine Pittsburgh PA USA

Department of Medicine Division of Oncology Stanford Cancer Institute Stanford University School of Medicine Stanford CA USA

Department of Medicine Huntsman Cancer Institute Salt Lake City UT USA

Department of Medicine Magee Womens Hospital University of Pittsburgh School of Medicine Pittsburgh PA USA

Department of Medicine McGill University Montréal Québec Canada

Department of Molecular Genetics National Institute of Oncology Budapest Hungary

Department of Molecular Genetics University of Toronto Toronto Ontario Canada

Department of Molecular Medicine and Surgery Karolinska Institutet Stockholm Sweden

Department of Non Communicable Disease Epidemiology London School of Hygiene and Tropical Medicine London UK

Department of Obstetrics and Gynecology and Comprehensive Cancer Center Medical University of Vienna Vienna Austria

Department of Obstetrics and Gynecology Helsinki University Hospital University of Helsinki Helsinki Finland

Department of Obstetrics and Gynecology Medical University of Vienna Vienna Austria

Department of Oncology Helsinki University Hospital University of Helsinki Helsinki Finland

Department of Oncology Lund University and Skåne University Hospital Lund Sweden

Department of Oncology Örebro University Hospital Örebro Sweden

Department of Oncology Södersjukhuset Stockholm Sweden

Department of Oncology Tampere University Hospital Tampere University and Tampere Cancer Center Tampere Finland

Department of Oncology University Hospital of Larissa Larissa Greece

Department of Pathology and Laboratory Medicine Kansas University Medical Center Kansas City KS USA

Department of Pathology Landspitali University Hospital Reykjavik Iceland

Department of Pathology Leiden University Medical Center Leiden the Netherlands

Department of Pathology School of Medicine Umm Al Qura University Holy Makkah Saudi Arabia

Department of Pathology University Hospital of Heraklion Heraklion Greece

Department of Population Sciences Beckman Research Institute of City of Hope Duarte CA USA

Department of Preventive Medicine Keck School of Medicine University of Southern California Los Angeles CA USA

Department of Preventive Medicine Seoul National University College of Medicine Seoul Korea

Department of Public Health Sciences and Cancer Research Institute Queen's University Kingston Ontario Canada

Department of Radiation Oncology Hannover Medical School Hannover Germany

Department of Surgery Faculty of Medicine University of Malaya Kuala Lumpur Malaysia

Department of Surgery Hong Kong Sanatorium and Hospital Happy Valley Hong Kong

Department of Surgery Leiden University Medical Center Leiden the Netherlands

Department of Surgery National University Health System Singapore Singapore

Department of Surgery Oulu University Hospital University of Oulu Oulu Finland

Department of Surgery The University of Hong Kong Pok Fu Lam Hong Kong

Department of Surgical Sciences Uppsala University Uppsala Sweden

Department of Tumour Biology INSERM U830 Paris France

Departments of Pediatrics and Medicine Columbia University New York NY USA

Discipline of Medical Genetics School of Biomedical Sciences and Pharmacy Faculty of Health University of Newcastle Newcastle New South Wales Australia

Division of Breast Cancer Research The Institute of Cancer Research London UK

Division of Cancer Epidemiology and Genetics Department of Health and Human Services National Cancer Institute National Institutes of Health Bethesda MD USA

Division of Cancer Epidemiology and Prevention Aichi Cancer Center Research Institute Nagoya Japan

Division of Cancer Epidemiology German Cancer Research Center Heidelberg Germany

Division of Cancer Epidemiology Nagoya University Graduate School of Medicine Nagoya Japan

Division of Cancer Prevention and Genetics European Institute of Oncology IRCCS Milan Italy

Division of Cancer Sciences University of Manchester Manchester UK

Division of Clinical Epidemiology and Aging Research Heidelberg Germany

Division of Clinical Epidemiology Royal Victoria Hospital McGill University Montréal Québec Canada

Division of Epidemiology Center for Public Health Sciences National Cancer Center Tokyo Japan

Division of Epidemiology Department of Medicine Vanderbilt Epidemiology Center Vanderbilt Ingram Cancer Center Vanderbilt University School of Medicine Nashville TN USA

Division of Evolution and Genomic Sciences School of Biological Sciences Faculty of Biology Medicine and Health The University of Manchester Manchester Academic Health Science Centre Manchester UK

Division of Functional Onco genomics and Genetics Centro di Riferimento Oncologico di Aviano IRCCS Aviano Italy

Division of Genetics and Epidemiology Institute of Cancer Research London UK

Division of Genetics and Epidemiology The Institute of Cancer Research London UK

Division of Molecular Medicine Pathology North John Hunter Hospital Newcastle New South Wales Australia

Division of Molecular Pathology Netherlands Cancer Institute Antoni van Leeuwenhoek Hospital Amsterdam the Netherlands

Division of Population Health Health Services Research and Primary Care School of Health Sciences Faculty of Biology Medicine and Health The University of Manchester Manchester UK

Division of Preventive Oncology German Cancer Research Center Heidelberg Germany

Division of Psychosocial Research and Epidemiology The Netherlands Cancer Institute Antoni van Leeuwenhoek Hospital Amsterdam the Netherlands

Dr Margarete Fischer Bosch Institute of Clinical Pharmacology Stuttgart Germany

Epidemiology Branch National Institute of Environmental Health Sciences National Institutes of Health Research Triangle Park NC USA

Epigenetic and Stem Cell Biology Laboratory National Institute of Environmental Health Sciences National Institutes of Health Research Triangle Park NC USA

Faculty of Health and Medical Sciences University of Copenhagen Copenhagen Denmark

Faculty of Information Technology Monash University Melbourne Victoria Australia

Faculty of Medicine University of Heidelberg Heidelberg Germany

Faculty of Medicine University of Southampton Southampton UK

Familial Cancer Service Weatmead Hospital Sydney New South Wales Australia

Family Cancer Clinic The Netherlands Cancer Institute Antoni van Leeuwenhoek Hospital Amsterdam the Netherlands

Frauenklinik der Stadtklinik Baden Baden Baden Baden Germany

Fred A Litwin Center for Cancer Genetics Lunenfeld Tanenbaum Research Institute Mount Sinai Hospital Toronto Ontario Canada

Fundación Pública Galega de Medicina Xenómica Santiago de Compostela Spain

Fundación Pública Galega de Medicina Xenómica SERGAS Grupo de Medicina Xenómica USC CIBERER IDIS Santiago de Compostela Spain

Genetic Epidemiology of Cancer Team INSERM U900 Paris France

Genome Diagnostics Program IFOM the FIRC Institute of Molecular Oncology Milan Italy

Genome Sciences Centre BC Cancer Agency Vancouver British Columbia Canada

Genomic Epidemiology Group German Cancer Research Center Heidelberg Germany

Genomic Medicine Group Galician Foundation of Genomic Medicine Instituto de Investigación Sanitaria de Santiago de Compostela Complejo Hospitalario Universitario de Santiago SERGAS Santiago de Compostela Spain

Genomics Center Centre Hospitalier Universitaire de Québec Université Laval Research Center Québec City Québec Canada

German Cancer Consortium Heidelberg Germany

Gynaecology Research Unit Hannover Medical School Hannover Germany

Hematology Oncology and Transfusion Medicine Center Department of Molecular and Regenerative Medicine Vilnius University Hospital Santariskiu Clinics Vilnius Lithuania

Hereditary Cancer Program ONCOBELL IDIBELL IDIBGI IGTP Catalan Institute of Oncology CIBERONC Barcelona Spain

High Risk and Cancer Prevention Group Vall Hebron Institute of Oncology Barcelona Spain

Hong Kong Hereditary Breast Cancer Family Registry Cancer Genetics Centre Happy Valley Hong Kong

Human Cancer Genetics Programme Spanish National Cancer Research Centre Madrid Spain

Human Genotyping CEGEN Unit Human Cancer Genetic Program Spanish National Cancer Research Centre Madrid Spain

Hunter Medical Research Institute John Hunter Hospital Newcastle New South Wales Australia

iFIT Cluster of Excellence University of Tuebingen Tuebingen Germany

Imaging Center Department of Clinical Pathology Kuopio University Hospital Kuopio Finland

Immunology and Molecular Oncology Unit Veneto Institute of Oncology IRCCS Padua Italy

Independent Laboratory of Molecular Biology and Genetic Diagnostics Pomeranian Medical University Szczecin Poland

Institut Curie Paris France

Institute for Medical Informatics Statistics and Epidemiology University of Leipzig Leipzig Germany

Institute for Prevention and Occupational Medicine of the German Social Accident Insurance Institute of the Ruhr University Bochum Bochum Germany

Institute of Biochemistry and Genetics Ufa Federal Research Centre of the Russian Academy of Sciences Ufa Russia

Institute of Biomedical Sciences Academia Sinica Taipei Taiwan

Institute of Cancer and Genomic Sciences University of Birmingham Birmingham UK

Institute of Clinical Medicine Faculty of Medicine University of Oslo Oslo Norway

Institute of Clinical Medicine Oncology University of Eastern Finland Kuopio Finland

Institute of Clinical Medicine Pathology and Forensic Medicine University of Eastern Finland Kuopio Finland

Institute of Environmental Medicine Karolinska Institutet Stockholm Sweden

Institute of Human Genetics Hannover Medical School Hannover Germany

Institute of Human Genetics Pontificia Universidad Javeriana Bogota Colombia

Institute of Human Genetics University Hospital Heidelberg Heidelberg Germany

Institute of Medical Genetics and Applied Genomics University of Tübingen Tübingen Germany

Instituto de Investigación Sanitaria de Santiago de Compostela Santiago de Compostela Spain

International Epidemiology Institute Rockville MD USA

Laboratory for Translational Genetics Department of Human Genetics University of Leuven Leuven Belgium

Laboratory Medicine Program University Health Network Toronto Ontario Canada

Laboratory of Cancer Genetics and Tumor Biology Cancer and Translational Medicine Research Unit Biocenter Oulu University of Oulu Oulu Finland

Laboratory of Cancer Genetics and Tumor Biology Northern Finland Laboratory Centre Oulu Oulu Finland

Latvian Biomedical Research and Study Centre Riga Latvia

Leuven Multidisciplinary Breast Center Department of Oncology Leuven Cancer Institute University Hospitals Leuven Leuven Belgium

Lombardi Comprehensive Cancer Center Georgetown University Washington DC USA

Medical Faculty Universidad de La Sabana Bogota Colombia

Medical Oncology Department Hospital Clínico San Carlos Instituto de Investigación Sanitaria San Carlos Madrid Spain

Medical Oncology Department Hospital Universitario Puerta de Hierro Madrid Spain

Mines ParisTech Paris France

Molecular Biology of Breast Cancer University Womens Clinic Heidelberg University of Heidelberg Heidelberg Germany

Molecular Diagnostics Aalborg University Hospital Aalborg Denmark

Molecular Diagnostics Laboratory INRASTES National Centre for Scientific Research 'Demokritos' Athens Greece

Molecular Epidemiology Group Heidelberg Germany

Molecular Genetics of Breast Cancer German Cancer Research Center Heidelberg Germany

Molecular Oncology Laboratory CIBERONC Hospital Clinico San Carlos Instituto de Investigación Sanitaria del Hospital Clínico San Carlos Madrid Spain

Moores Cancer Center University of California San Diego La Jolla CA USA

N N Alexandrov Research Institute of Oncology and Medical Radiology Minsk Belarus

N N Petrov Institute of Oncology St Petersburg Russia

National Center for Tumor Diseases University Hospital and German Cancer Research Center Heidelberg Germany

Network Aging Research University of Heidelberg Heidelberg Germany

North West Genomics Laboratory Hub Manchester Centre for Genomic Medicine St Mary's Hospital Manchester University NHS Foundation Trust Manchester Academic Health Science Centre Manchester UK

NRG Oncology Statistics and Data Management Center Roswell Park Cancer Institute Buffalo NY USA

Nuffield Department of Population Health University of Oxford Oxford UK

Oncogenetics Group Vall d'Hebron Institute of Oncology Barcelona Spain

Oncology and Genetics Unit Instituto de Investigacion Sanitaria Galicia Sur Xerencia de Xestion Integrada de Vigo SERGAS Vigo Spain

Parkville Familial Cancer Centre Peter MacCallum Cancer Center Melbourne Victoria Australia

Population Oncology BC Cancer Vancouver British Columbia Canada

Precision Medicine School of Clinical Sciences at Monash Health Monash University Melbourne Victoria Australia

ProCURE Catalan Institute of Oncology Bellvitge Biomedical Research Institute Barcelona Spain

Program in Cancer Genetics Departments of Human Genetics and Oncology McGill University Montréal Québec Canada

Program in Genetic Epidemiology and Statistical Genetics Harvard T H Chan School of Public Health Boston MA USA

Radiation Epidemiology Branch Division of Cancer Epidemiology and Genetics National Cancer Institute Bethesda MD USA

Radiation Oncology Hospital Meixoeiro XXI de Vigo Vigo Spain

Research Centre for Genetic Engineering and Biotechnology 'Georgi D Efremov' Macedonian Academy of Sciences and Arts Skopje Republic of North Macedonia

Research Department Peter MacCallum Cancer Center Melbourne Victoria Australia

Research Oncology Guy's Hospital King's College London London UK

Sackler Faculty of Medicine Tel Aviv University Ramat Aviv Israel

Saw Swee Hock School of Public Health National University of Singapore Singapore Singapore

School of Life Sciences University of Westminster London UK

School of Medicine University of Western Australia Perth Western Australia Australia

School of Population and Global Health The University of Western Australia Perth Western Australia Australia

School of Population and Public Health University of British Columbia Vancouver British Columbia Canada

School of Public Health China Medical University Taichung Taiwan

School of Public Health Curtin University Perth Western Australia Australia

School of Women's and Children's Health Faculty of Medicine University of New South Wales Sydney New South Wales Australia

Schools of Medicine and Public Health Division of Cancer Prevention and Control Research Jonsson Comprehensive Cancer Centre University of California Los Angeles Los Angeles CA USA

Service de Génétique Institut Curie Paris France

Sheffield Institute for Nucleic Acids Department of Oncology and Metabolism University of Sheffield Sheffield UK

Sir Peter MacCallum Department of Oncology The University of Melbourne Melbourne Victoria Australia

SOD Genetica Molecolare University Hospital Pisa Italy

Southampton Clinical Trials Unit Faculty of Medicine University of Southampton Southampton UK

State Research Institute Centre for Innovative Medicine Vilnius Lithuania

Surgery School of Medicine National University of Ireland Galway Ireland

The Curtin UWA Centre for Genetic Origins of Health and Disease Curtin University and University of Western Australia Perth Western Australia Australia

The Hereditary Breast and Ovarian Cancer Research Group Netherlands Coordinating Center The Netherlands Cancer Institute Amsterdam the Netherlands

The Kinghorn Cancer Centre Garvan Institute of Medical Research Sydney New South Wales Australia

The Suzanne Levy Gertner Oncogenetics Unit Chaim Sheba Medical Center Ramat Gan Israel

The University of Chicago Pritzker School of Medicine Chicago IL USA

Translational Cancer Research Area University of Eastern Finland Kuopio Finland

U O Anatomia Patologica Ospedale di Circolo ASST Settelaghi Varese Italy

UK Dementia Research Institute Imperial College London London UK

Unit of Medical Genetics Department of Medical Oncology and Hematology Fondazione IRCCS Istituto Nazionale dei Tumori di Milano Milan Italy

Unit of Molecular Bases of Genetic Risk and Genetic Testing Department of Research Fondazione IRCCS Istituto Nazionale dei Tumori Milan Italy

Université Paris Descartes Paris France

University Clinic of Radiotherapy and Oncology Medical Faculty Ss Cyril and Methodius University in Skopje Skopje Republic of North Macedonia

University of New Mexico Health Sciences Center University of New Mexico Albuquerque NM USA

VIB Center for Cancer Biology VIB Leuven Belgium

Wellcome Trust Centre for Human Genetics and NIHR Oxford Biomedical Research Centre University of Oxford Oxford UK

Westmead Institute for Medical Research University of Sydney Sydney New South Wales Australia

Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute Cedars Sinai Medical Center Los Angeles CA USA

Women's College Research Institute University of Toronto Toronto Ontario Canada

Zilber School of Public Health University of Wisconsin Milwaukee Milwaukee WI USA

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Large-Scale Alternative Polyadenylation-Wide Association Studies to Identify Putative Cancer Susceptibility Genes

Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes

Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

Epigenetic Research in Stem Cell Bioengineering-Anti-Cancer Therapy, Regenerative and Reconstructive Medicine in Human Clinical Trials