Prime Editing: A New Way for Genome Editing
Language English Country Great Britain, England Media print-electronic
Document type Journal Article
PubMed
32001098
DOI
10.1016/j.tcb.2020.01.004
PII: S0962-8924(20)30015-5
Knihovny.cz E-resources
- Keywords
- CRISPR-Cas9, genome editing, prime editing, targeted mutagenesis,
- MeSH
- DNA genetics MeSH
- Gene Editing * MeSH
- Hybridization, Genetic MeSH
- Humans MeSH
- RNA, Guide, CRISPR-Cas Systems genetics MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- DNA MeSH
- RNA, Guide, CRISPR-Cas Systems MeSH
Precise and efficient use of genome editing tools are hampered by the introduction of DNA double-strand breaks, donor DNA templates, or homology-directed repair. A recent study expands the genome editing toolbox with the introduction of prime editing, which overcomes previous challenges and introduces insertions, deletions, and all putative 12 types of base-to-base conversions in human cells.
References provided by Crossref.org
OMICs, Epigenetics, and Genome Editing Techniques for Food and Nutritional Security
