Recent years have witnessed much progress in medical device manufacturing and the needs of the medical industry urges modern nanomaterials science to develop novel approaches for improving the properties of existing biomaterials. One of the ways to enhance the material properties is their nanostructuring by using severe plastic deformation (SPD) techniques. For medical devices, such properties include increased strength and fatigue life, and this determines nanostructured Ti and Ti alloys to be an excellent choice for the engineering of implants with improved design for orthopedics and dentistry. Various reported studies conducted in this field enable the fabrication of medical devices with enhanced functionality. This paper reviews recent development in the field of nanostructured Ti-based materials and provides examples of the use of ultra-fine grained Ti alloys in medicine.

Department of Physics of Materials Charles University Ke Karlovu 3 121 16 Prague Czech Republic

Department of Traumatology and Orthopedics Bashkir State Medical University 3 Lenin street 450008 Ufa Russia

Institute of Physics of Advanced Materials Ufa State Aviation Technical University 12 K Marx street 450008 Ufa Russia

Laboratory of Mechanics of Advanced Bulk Nanomaterials Saint Petersburg State University Universitetskiy prospekt 28 Peterhof 198504 St Petersburg Russia

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