Photodynamic-active smart biocompatible material for an antibacterial surface coating
Language English Country Switzerland Media print-electronic
Document type Journal Article
PubMed
32919175
DOI
10.1016/j.jphotobiol.2020.112012
PII: S1011-1344(20)30462-0
Knihovny.cz E-resources
- Keywords
- Antibacterial activity, Hydrophobic carbon quantum dots, Nanocomposite, Photodynamic therapy, Radicals,
- MeSH
- Anti-Bacterial Agents chemistry MeSH
- Biofilms MeSH
- Coated Materials, Biocompatible chemistry MeSH
- Smart Materials chemistry MeSH
- Photosensitizing Agents chemistry MeSH
- Hydrophobic and Hydrophilic Interactions MeSH
- Quantum Dots chemistry MeSH
- Mice MeSH
- Surface Properties MeSH
- Reactive Oxygen Species metabolism MeSH
- Singlet Oxygen chemistry MeSH
- Staphylococcus aureus MeSH
- Carbon chemistry MeSH
- Cell Survival drug effects MeSH
- Animals MeSH
- Check Tag
- Mice MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Anti-Bacterial Agents MeSH
- Coated Materials, Biocompatible MeSH
- Smart Materials MeSH
- Photosensitizing Agents MeSH
- Reactive Oxygen Species MeSH
- Singlet Oxygen MeSH
- Carbon MeSH
Here we present a new effective antibacterial material suitable for a coating, e.g., surface treatment of textiles, which is also time and financially undemanding. The most important role is played by hydrophobic carbon quantum dots, as a new type of photosensitizer, produced by carbonization of different carbon precursors, which are incorporated by swelling from solution into various polymer matrices in the form of thin films, in particular polyurethanes, which are currently commercially used for industrial surface treatment of textiles. The role of hydrophobic carbon quantum dots is to work as photosensitizers upon irradiation and produce reactive oxygen species, namely singlet oxygen, which is already known as the most effective radical for elimination different kinds of bacteria on the surface or in close proximity to such modified material. Therefore, we have mainly studied the effect of hydrophobic carbon quantum dots on Staphylococcus aureus and the cytotoxicity tests, which are essential for the safe handling of such material. Also, the production of singlet oxygen by several methods (electron paramagnetic spectroscopy, time-resolved near-infrared spectroscopy), surface structures (atomic force microscopy and contact angle measurement), and the effect of radiation on polymer matrices were studied. The prepared material is easily modulated by end-user requirements.
Centre of Polymer Systems Tomas Bata University in Zlín Třída Tomáše Bati 5678 Zlín Czech Republic
Institute of Physics Slovak Academy of Sciences Dúbravská cesta 9 845 11 Bratislava Slovakia
Polymer Institute Slovak Academy of Sciences Dúbravská cesta 9 845 41 Bratislava 45 Slovakia
Vinca Institute of Nuclear Sciences Mike Alasa 12 14 Vinca 11351 Belgrade Serbia
References provided by Crossref.org
Multi-Hollow Surface Dielectric Barrier Discharge for Bacterial Biofilm Decontamination