A review on advances in graphene-derivative/polysaccharide bionanocomposites: Therapeutics, pharmacogenomics and toxicity
Jazyk angličtina Země Velká Británie, Anglie Médium print-electronic
Typ dokumentu časopisecké články, přehledy
PubMed
33049857
DOI
10.1016/j.carbpol.2020.116952
PII: S0144-8617(20)31125-5
Knihovny.cz E-zdroje
- Klíčová slova
- Antimicrobial therapy, Co-delivery, Drug delivery, Graphene oxide nanocomposites, Polysaccharide Bionanocomposites,
- MeSH
- antitumorózní látky chemie farmakologie MeSH
- farmakogenetika * MeSH
- grafit chemie MeSH
- lidé MeSH
- nádory farmakoterapie genetika patologie MeSH
- nanokompozity aplikace a dávkování chemie MeSH
- nežádoucí účinky léčiv etiologie patologie MeSH
- polysacharidy chemie farmakologie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
- Názvy látek
- antitumorózní látky MeSH
- grafit MeSH
- polysacharidy MeSH
Graphene-based bionanocomposites are employed in several ailments, such as cancers and infectious diseases, due to their large surface area (to carry drugs), photothermal properties, and ease of their functionalization (owing to their active groups). Modification of graphene-derivatives with polysaccharides is a promising strategy to decrease their toxicity and improve target ability, which consequently enhances their biotherapeutic efficacy. Herein, functionalization of graphene-based materials with carbohydrate polymers (e.g., chitosan, starch, alginate, hyaluronic acid, and cellulose) are presented. Subsequently, recent advances in graphene nanomaterial/polysaccharide-based bionanocomposites in infection treatment and cancer therapy are comprehensively discussed. Pharmacogenomic and toxicity assessments for these bionanocomposites are also highlighted to provide insight for future optimized and smart investigations and researches.
Chemistry Department Faculty of Science Shahid Chamran University of Ahvaz Ahvaz 6153753843 Iran
Department of Biotechnology Indian Institute of Technology Kharagpur 721302 India
Department of Chemical Sciences University of Naples Federico 2 Naples 80126 Italy
School of Chemistry Damghan University Damghan 36716 41167 Iran
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