Heterotopic acinic cell carcinoma and its clinical implications
Language English Country Czech Republic Media print-electronic
Document type Journal Article, Review
PubMed
33177745
DOI
10.5507/bp.2020.047
Knihovny.cz E-resources
- Keywords
- acinic cell carcinoma, heterotopia, lymph node, salivary gland,
- MeSH
- Carcinoma, Acinar Cell * diagnosis therapy MeSH
- Humans MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
This is a review of the clinical and histopathological published data on very rare heterotopic acinic cell carcinomas (AcCCs) with suggested optimal management. Extrasalivary AcCCs originate primarily in parotid lymph nodes. They present at low clinical stage, show mostly low-grade histopathology and are circumscribed with a complete nodal capsule. Extracapsular dissection was advocated as adequate therapy. In rare cases with positive surgical margins, a completion parotidectomy or adjuvant radiotherapy should follow. Heterotopic high-grade AcCCs are rare, necessitating radical surgery including neck dissection and adjuvant radiotherapy. The short term prognosis is excellent, long term outcomes are not known. Longer term follow-up is essential.
References provided by Crossref.org