Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019: A Systematic Analysis for the Global Burden of Disease Study 2019

. 2022 Mar 01 ; 8 (3) : 420-444.

Jazyk angličtina Země Spojené státy americké Médium print

Typ dokumentu časopisecké články, práce podpořená grantem, systematický přehled

Perzistentní odkaz   https://www.medvik.cz/link/pmid34967848

Grantová podpora
001 World Health Organization - International
SCAF/15/02 Chief Scientist Office - United Kingdom
SPHSU17 Chief Scientist Office - United Kingdom
MC_UU_00022/2 Medical Research Council - United Kingdom

IMPORTANCE: The Global Burden of Diseases, Injuries, and Risk Factors Study 2019 (GBD 2019) provided systematic estimates of incidence, morbidity, and mortality to inform local and international efforts toward reducing cancer burden. OBJECTIVE: To estimate cancer burden and trends globally for 204 countries and territories and by Sociodemographic Index (SDI) quintiles from 2010 to 2019. EVIDENCE REVIEW: The GBD 2019 estimation methods were used to describe cancer incidence, mortality, years lived with disability, years of life lost, and disability-adjusted life years (DALYs) in 2019 and over the past decade. Estimates are also provided by quintiles of the SDI, a composite measure of educational attainment, income per capita, and total fertility rate for those younger than 25 years. Estimates include 95% uncertainty intervals (UIs). FINDINGS: In 2019, there were an estimated 23.6 million (95% UI, 22.2-24.9 million) new cancer cases (17.2 million when excluding nonmelanoma skin cancer) and 10.0 million (95% UI, 9.36-10.6 million) cancer deaths globally, with an estimated 250 million (235-264 million) DALYs due to cancer. Since 2010, these represented a 26.3% (95% UI, 20.3%-32.3%) increase in new cases, a 20.9% (95% UI, 14.2%-27.6%) increase in deaths, and a 16.0% (95% UI, 9.3%-22.8%) increase in DALYs. Among 22 groups of diseases and injuries in the GBD 2019 study, cancer was second only to cardiovascular diseases for the number of deaths, years of life lost, and DALYs globally in 2019. Cancer burden differed across SDI quintiles. The proportion of years lived with disability that contributed to DALYs increased with SDI, ranging from 1.4% (1.1%-1.8%) in the low SDI quintile to 5.7% (4.2%-7.1%) in the high SDI quintile. While the high SDI quintile had the highest number of new cases in 2019, the middle SDI quintile had the highest number of cancer deaths and DALYs. From 2010 to 2019, the largest percentage increase in the numbers of cases and deaths occurred in the low and low-middle SDI quintiles. CONCLUSIONS AND RELEVANCE: The results of this systematic analysis suggest that the global burden of cancer is substantial and growing, with burden differing by SDI. These results provide comprehensive and comparable estimates that can potentially inform efforts toward equitable cancer control around the world.

Academic Unit of Obstetrics and Gynecology University of Genoa Genoa Italy

Addictology Department Russian Medical Academy of Continuous Professional Education Moscow Russia

Adelaide Medical School University of Adelaide Adelaide South Australia Australia

Administrative and Economic Sciences Department University of Bucharest Bucharest Romania

Advanced Diagnostic and Interventional Radiology Research Center Tehran University of Medical Sciences Tehran Iran

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Afro Asian Institute Lahore Pakistan

Al Shifa School of Public Health Al Shifa Trust Eye Hospital Rawalpindi Pakistan

Allied Health Sciences Khyber Medical University Timergara Lower Dir Pakistan

Alzahra Teaching Hospital Tabriz University of Medical Sciences Tabriz Iran

Amity Institute of Biotechnology Amity University Rajasthan Jaipur India

Applied Biomedical Research Center Mashhad University of Medical Sciences Mashhad Iran

Arthritis Research Canada Richmond British Columbia Canada

Asbestos Diseases Research Institute Sydney New South Wales Australia

Asbestos Diseases Research Institute University of Sydney Sydney New South Wales Australia

Associated Laboratory for Green Chemistry University of Porto Porto Portugal

Bahir Dar University Bahir Dar Ethiopia

Barcelona Institute for Global Health Barcelona Spain

Basic Medical Sciences Department Durban University of Technology Durban South Africa

Beijing Institute of Ophthalmology Beijing Tongren Hospital Beijing China

Biological Production Development National Institute of Health Islamabad Pakistan

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Harrington Heart and Vascular Institute Case Western Reserve University Cleveland Ohio

Health Behavior and Society Jimma University Jimma Ethiopia

Health Emergency Operation Center Ministry of Health and Population Kathmandu Nepal

Health Informatic Lab Boston University Boston Massachusetts

Health Informatics Department Nursing and Midwifery Faculty Hanoi Medical University Ha Noi Vietnam

Health Management and Economics Research Center Iran University of Medical Sciences Tehran Iran

Health Research Section Nepal Health Research Council Kathmandu Nepal

Health Services Management Department Qazvin University of Medical Sciences Qazvin Iran

Health Services Management Training Centre Semmelweis University Budapest Hungary

Health Systems and Policy Research Indian Institute of Public Health Gandhinagar India

Health Systems and Policy Research Unit Ahmadu Bello University Zaria Nigeria

Health Systems Research Center National Institute of Public Health Cuernavaca Mexico

Heidelberg Institute of Global Health Heidelberg University Heidelberg Germany

HIV STI Surveillance Research Center and World Health Organization Collaborating Center for HIV Surveillance Kerman University of Medical Sciences Kerman Iran

Hospitalist Department Geisinger Health System Danville Pennsylvania

Hudson College of Public Health University of Oklahoma Health Sciences Center Oklahoma City

Human Biology Division Fred Hutchinson Cancer Research Center Seattle Washington

Hunter New England Population Health Wallsend New South Wales Australia

Independent Consultant Karachi Pakistan

Independent Consultant Santa Clara California

India Cancer Research Consortium Indian Council of Medical Research New Delhi India

Indian Council of Medical Research New Delhi India

Indonesian Public Health Association Surabaya Indonesia

Institute for Cancer Research Prevention and Clinical Network Florence Italy

Institute for Epidemiology and Social Medicine University of Münster Münster Germany

Institute for Global Health Innovations Duy Tan University Hanoi Vietnam

Institute for Health Metrics and Evaluation University of Washington Seattle

Institute for Physical Activity and Nutrition Deakin University Burwood Victoria Australia

Institute for Prevention of Non communicable Diseases Qazvin University of Medical Sciences Qazvin Iran

Institute for Research and Innovation in Health University of Porto Porto Portugal

Institute for Risk Assessment Sciences Utrecht University Utrecht Netherlands

Institute for Women's Health University College London London England

Institute of Biomedical Engineering University of Porto Porto Portugal

Institute of Clinical Physiology National Research Council Pisa Italy

Institute of Comparative Economic Studies Hosei University Tokyo Japan

Institute of Family Medicine and Public Health University of Tartu Tartu Estonia

Institute of Gerontological Health Services and Nursing Research Ravensburg Weingarten University of Applied Sciences Weingarten Germany

Institute of Health and Society University of Oslo Oslo Norway

Institute of Health Policy and Management Seoul National University Seoul South Korea

Institute of Health Services Research Yonsei University Seoul South Korea

Institute of Microengineering Federal Polytechnic School of Lausanne Lausanne Switzerland

Institute of Pharmaceutical Sciences University of Veterinary and Animal Sciences Lahore Pakistan

Institute of Public Health United Arab Emirates University Al Ain United Arab Emirates

Institute of Radiological Sciences and Medical Imaging Technology University of Lahore Lahore Pakistan

Institute of Research and Development Duy Tan University Da Nang Vietnam

Institute of Soil and Environmental Sciences University of Agriculture Faisalabad Faisalabad Pakistan

Internal Medicine Department Carol Davila University of Medicine and Pharmacy Bucharest Romania

Internal Medicine Department King Saud University Riyadh Saudi Arabia

Internal Medicine University of Kentucky Lexington

International Centre for Casemix and Clinical Coding National University of Malaysia Bandar Tun Razak Malaysia

International Foundation for Dermatology London England

International Islamic University Islamabad Islamabad Pakistan

Iran University of Medical Sciences Tehran Iran

James Cancer Hospital Ohio State University Columbus

Jockey Club School of Public Health and Primary Care Chinese University of Hong Kong Hong Kong China

John T Milliken Department of Internal Medicine Washington University in St Louis St Louis Missouri

Johns Hopkins University Baltimore Maryland

Kasturba Medical College Mangalore Manipal Academy of Higher Education Manipal India

Kasturba Medical College Manipal Academy of Higher Education Mangalore India

Kasturba Medical College Udupi India

Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research Stomatological Hospital of Xi'an Jiaotong University Xi'an China

Laboratory for Process Engineering Environment Biotechnology and Energy University of Porto Porto Portugal

Laboratory of Genetics and Genomics Moscow Research and Practical Centre on Addictions Moscow Russia

Laboratory of Public Health Indicators Analysis and Health Digitalization Moscow Institute of Physics and Technology Dolgoprudny Russia

Laboratory Technology Sciences Department Yasouj University Yasuj Iran

Lerner Research Institute Cleveland Clinic Cleveland Ohio

Liver and Pancreaticobilliary Disease Research Center Tehran University of Medical Sciences Tehran Iran

Manipal Academy of Higher Education Manipal India

Manipal College of Dental Sciences Manipal Academy of Higher Education Manipal India

Market Access Bayer Istanbul Turkey

Mary MacKillop Institute for Health Research Australian Catholic University Melbourne Victoria Australia

Mass Communication Department Ajman University Dubai United Arab Emirates

Mass Communication Department University of Sharjah Sharjah United Arab Emirates

Maternal and Child Health Projahnmo Research Foundation Dhaka Bangladesh

Maurizio Bufalini Hospital Cesena Italy

Mayo Evidence Based Practice Center Mayo Clinic Foundation for Medical Education and Research Rochester Minnesota

McGovern Medical School University of Texas Houston

Medical Research Council Chief Scientist Office Social and Public Health Sciences Unit University of Glasgow Glasgow Scotland

Medical Research Council Clinical Trials Unit University College London London England

Medicine Service Department of Veterans Affairs Birmingham Alabama

Metabolomics and Genomics Research Center Tehran University of Medical Sciences Tehran Iran

Microbial Cellular and Molecular Biology Addis Ababa University Addis Ababa Ethiopia

Microbiology and Molecular Cell Biology Department Eastern Virginia Medical School Norfolk

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Minimally Invasive Surgery Research Center Iran University of Medical Sciences Tehran Iran

Ministry of Health Herrera Panama

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National Centre for Disease Informatics and Research Indian Council of Medical Research Bengaluru India

National Health Service London England

National Heart Lung and Blood Institute National Institutes of Health Rockville Maryland

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National Institute for Health Research Global Health Research Unit on Global Surgery University of Birmingham Birmingham England

National Institute of Infectious Diseases Bucuresti Romania

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Office of Health Policy and Legislative Affairs University of Texas Galveston

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Oncology Department Appalachian Regional Healthcare Hazard Kentucky

One Health University of Nantes Nantes France

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Pars Hospital Iran University of Medical Sciences Tehran Iran

Pathology and Laboratory Medicine Institute Cleveland Clinic Cleveland Ohio

Pathology Department Alexandria University Alexandria Egypt

Pattern Recognition and Machine Learning Lab Gachon University Seongnam South Korea

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Pediatric Services King Hussein Cancer Center Amman Jordan

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Pediatrics University of Jordan Amman Jordan

Peru Country Office United Nations Population Fund Lima Peru

Pharmaceutical Outcomes and Policy Department University of Florida Gainesville

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Pharmacy Department Carol Davila University of Medicine and Pharmacy Bucharest Romania

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Razi Vaccine and Serum Research Institute Agricultural Research Education and Extension Organization Tehran Iran

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Research and Analytics Department Initiative for Financing Health and Human Development Chennai India

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Research Center for Immunodeficiencies Tehran University of Medical Sciences Tehran Iran

Research Center for Molecular Medicine Hamadan University of Medical Sciences Hamadan Iran

Research Division Association for Biodiversity Conservation and Research Balasore India

Research Group for Genomic Epidemiology Technical University of Denmark Copenhagen Denmark

Research Group in Health Economics University of Cartagena Cartagena Colombia

Research Group in Hospital Management and Health Policies Universidad de la Costa Barranquilla Colombia

Research Line in Environmental Exposures and Health Effects at Population Level Centro de Desarrollo Urbano Sustentable Santiago Chile

Research Section Nepal Health Research Council Kathmandu Nepal

Research Unit on Applied Molecular Biosciences University of Porto Porto Portugal

Research Unit University of Barcelona Barcelona Spain

Rumailah Hospital Hamad Medical Corporation Doha Qatar

Russian Institute for Advanced Study Moscow State Pedagogical University Moscow Russia

San Martin de Porres University Lima Peru

Save Sight Institute University of Sydney Sydney New South Wales Australia

Saveetha Medical College Saveetha University Chennai India

Schiller Institute Boston College Boston Massachusetts

School of Advanced Technologies in Medicine Shahid Beheshti University of Medical Sciences Tehran Iran

School of Business London South Bank University London England

School of Business University of Leicester Leicester England

School of Community Health Charles Sturt University Orange New South Wales Australia

School of Economics and Business University of Groningen Groningen Netherlands

School of Health and Environmental Studies Hamdan Bin Mohammed Smart University Dubai United Arab Emirates

School of Health Guilan University of Medical Sciences Rasht Iran

School of Health Polytechnic Institute of Porto Portugal

School of Health Sciences A T Still University Mesa Arizona

School of Health Sciences Kristiania University College Oslo Norway

School of Health University of Technology Sydney Sydney New South Wales Australia

School of International Development and Global Studies University of Ottawa Ottawa Ontario Canada

School of Management and Medical Informatics Tabriz University of Medical Sciences Tabriz Iran

School of Mathematical Sciences University of Science Malaysia Penang Malaysia

School of Medicine and Public Health University of Newcastle Newcastle New South Wales Australia

School of Medicine and Surgery University of Milan Bicocca Monza Italy

School of Medicine Deakin University Geelong Victoria Australia

School of Medicine Georgetown University Washington DC

School of Medicine Shahroud University of Medical Sciences Shahroud Iran

School of Medicine Tehran University of Medical Sciences Tehran Iran

School of Medicine Tsinghua University Beijing China

School of Medicine University of Alabama at Birmingham Birmingham

School of Medicine Western Sydney University Campbelltown New South Wales Australia

School of Nursing and Healthcare Professions Federation University Australia Berwick Victoria Australia

School of Nursing and Midwifery La Trobe University Melbourne Victoria Australia

School of Nursing Jimma University Jimma Ethiopia

School of Pharmaceutical Sciences University of Science Malaysia Penang Malaysia

School of Pharmacy Monash University Bandar Sunway Malaysia

School of Pharmacy Taipei Medical University Taipei Taiwan

School of Pharmacy Taylor's University Lakeside Campus Subang Jaya Malaysia

School of Physics Engineering and Computer Science University of Hertfordshire Hatfield England

School of Population and Public Health University of British Columbia Vancouver British Columbia Canada

School of Psychology Addis Ababa University Addis Ababa Ethiopia

School of Public Health All India Institute of Medical Sciences Jodhpur India

School of Public Health and Community Medicine University of Gothenburg Gothenburg Sweden

School of Public Health and Family Medicine University of Cape Town Cape Town South Africa

School of Public Health and Health Management University of Belgrade Belgrade Serbia

School of Public Health and Health Systems University of Waterloo Waterloo Ontario Canada

School of Public Health and Social Work Queensland University of Technology Brisbane Queensland Australia

School of Public Health Curtin University Perth Western Australia Australia

School of Public Health Mekelle University Mekelle Ethiopia

School of Public Health University of Adelaide Adelaide South Australia Australia

School of Public Health University of Hong Kong Hong Kong China

School of Public Health University of Nairobi Nairobi Kenya

School of Public Health Walailak University Nakhon Si Thammarat Thailand

School of Science and Technology University of Georgia Tbilisi Georgia

School of Traditional Chinese Medicine Xiamen University Malaysia Sepang Malaysia

Section of Plastic Surgery University of Michigan School of Medicine Ann Arbor

Section of Sustainable Health Umeå University Umea Sweden

Shahid Beheshti University of Medical Sciences Tehran Iran

Shahroud University of Medical Sciences Shahroud Iran

Sharjah Institute for Medical Research University of Sharjah Sharjah United Arab Emirates

Social and Environmental Health Research Nature Study Society of Bangladesh Khulna Bangladesh

Social Determinants of Health Research Center Babol University of Medical Sciences Babol Iran

Social Determinants of Health Research Center Birjand University of Medical Sciences Birjand Iran

Social Determinants of Health Research Center Kurdistan University of Medical Sciences Sanandaj Iran

Social Determinants of Health Research Center Lorestan University of Medical Sciences Khorramabad Iran

Social Determinants of Health Research Center Shahid Beheshti University of Medical Sciences Tehran Iran

South African Medical Research Council Cape Town South Africa

Southgate Institute for Health and Society Flinders University Adelaide South Australia Australia

St John's Institute of Dermatology King's College London London England

Student Research Committee Iran University of Medical Sciences Tehran Iran

Student Research Committee Tabriz University of Medical Sciences Tabriz Iran

Students Scientific Research Center Tehran University of Medical Sciences Tehran Iran

Suraj Eye Institute Nagpur India

Surgery Research Unit University of Oulu Oulu Finland

Sydney Eye Hospital South Eastern Sydney Local Health District Sydney New South Wales Australia

Sydney Medical School University of Sydney Sydney New South Wales Australia

Sydney School of Public Health University of Sydney Sydney New South Wales Australia

Symbiosis Medical College for Women Symbiosis International University Pune India

T H Chan School of Public Health Harvard University Boston Massachusetts

Terasaki Institute for Biomedical Innovation Los Angeles California

The Australian Centre for Public and Population Health Research University of Technology Sydney Sydney New South Wales Australia

The Iranian Academy of Medical Sciences Tehran Iran

The Judith Lumley Centre La Trobe University Melbourne Victoria Australia

Therapeutic Department Balashiha Central Hospital Balashikha Russia

Translational Health Research Institute Western Sydney University Campbelltown New South Wales Australia

Translational Health Research Institute Western Sydney University Sydney New South Wales Australia

Tropical Medicine Department Tanta University Tanta Egypt

Unit of Biochemistry Universiti Sultan Zainal Abidin Kuala Terengganu Malaysia

Unit of Genetics and Public Health Institute of Medical Sciences Las Tablas Panama

Unit of Microbiology and Public Health Institute of Medical Sciences Las Tablas Panama

University Centre Varazdin University North Varazdin Croatia

University Eye Clinic University of Genoa Genoa Italy

University Hospital Center of Porto University of Porto Porto Portugal

University Institute of Public Health University of Lahore Lahore Pakistan

University Medical Center Groningen University of Groningen Groningen Netherlands

University of Environment and Sustainable Development Somanya Ghana

University of Gondar Gondar Ethiopia

University of Malaya Medical Centre University of Malaya Kuala Lumpur Malaysia

University of Tasmania Tasmania Victoria Australia

University of Tokyo Tokyo Japan

University School of Management and Entrepreneurship Delhi Technological University Delhi India

Urology Department University of Florida Jacksonville

Urooncology Research Center Tehran University of Medical Sciences Tehran Iran

Victorian Comprehensive Cancer Centre Melbourne Victoria Australia

Vision and Eye Research Institute Anglia Ruskin University Cambridge England

Woman Mother Child Department Lausanne University Hospital Lausanne Switzerland

Women's Reproductive Health Research Center Tabriz University of Medical Sciences Tabriz Iran

Zayed University Abu Dhabi United Arab Emirates

Zoonoses Research Center Jahrom University of Medical Sciences Jahrom Iran

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