An efficient and versatile synthesis of the naturally occurring C-prenylated stilbenoid methyl ethers and their synthetic analogues is presented. The synthesis represents a six step convergent process including an optimised C-prenylation method. Furthermore, during the demethylation process, six new dihydro-benzopyranyl derivatives were obtained and isolated.

Department of Chemical Drugs Faculty of Pharmacy Masaryk University Palackeho tr 1946 1 612 00 Brno Czech Republic

Department of Natural Drugs Faculty of Pharmacy Masaryk University Palackeho tr 1946 1 612 00 Brno Czech Republic

Global Change Research Institute of the Czech Academy of Sciences Belidla 986 4a 603 00 Brno Czech Republic

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