Cyanine-flavonol hybrids as NIR-light activatable carbon monoxide donors in methanol and aqueous solutions
Jazyk angličtina Země Velká Británie, Anglie Médium electronic
Typ dokumentu časopisecké články
PubMed
35856793
DOI
10.1039/d2cc02648a
Knihovny.cz E-zdroje
- MeSH
- barvicí látky MeSH
- chinoliny * MeSH
- flavonoly MeSH
- methanol MeSH
- oxid uhelnatý * MeSH
- voda MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- barvicí látky MeSH
- chinoliny * MeSH
- flavonoly MeSH
- methanol MeSH
- oxid uhelnatý * MeSH
- voda MeSH
Here we report on carbon monoxide-photoreleasable compounds (photoCORMs) that combine heptamethine cyanine and flavonol chromophores and are activated upon irradiation with near-infrared light. Excellent CO-release yields and uncaging cross sections in aqueous solutions, enhanced water solubilities thanks to polar substituents or a host-guest approach using cucurbit[7]uril are demonstrated. The hybrids display outstanding biocompatibility and diverse, structure-dependent cell penetrability and internalization.
Department of Chemistry Faculty of Science Masaryk University Kamenice 5 625 00 Brno Czech Republic
RECETOX Faculty of Science Masaryk University Kamenice 5 625 00 Brno Czech Republic
Citace poskytuje Crossref.org
Visible-Light-Activated Carbon Monoxide Release from Porphyrin-Flavonol Hybrids
