The fifth edition of the World Health Organization (WHO) classification of urogenital tumours published in 2022 will be implemented in the European Association of Urology guidelines on renal cell carcinoma for 2023. Here we provide an update summarising changes in the new WHO classification of renal tumours from a clinician perspective.

Department of Cancer Medicine Gustave Roussy Université Paris Saclay Villejuif France

Department of Pathology and Laboratory Medicine Cumming School of Medicine University of Calgary and Alberta Precision Laboratories Calgary Canada

Department of Surgical and Perioperative Sciences Urology and Andrology Umeå University Umeå Sweden

Department of Translational Medicine Division of Urological Cancers Lund University Malmö Sweden

Department of Urology Cabueñes University Hospital Gijón Spain

Department of Urology Chaim Sheba Medical Center Tel Hashomer Ramat Gan Israel

Department of Urology Charité Universitätsmedizin Berlin Berlin Germany

Department of Urology Coimbra University Hospital Coimbra Portugal

Department of Urology Homerton University Hospital London UK

Department of Urology San Raffaele Scientific Institute Milan Italy; Division of Experimental Oncology Unit of Urology Urological Research Institute IRCCS San Raffaele Hospital Milan Italy

Department of Urology Sunderby Sjukhus Umeå University Luleå Sweden

Department of Urology University Hospital Pilsen and Faculty of Medicine in Pilsen Charles University Pilsen Czechia

Department of Urology University Hospital Tübingen Tübingen Germany; German Cancer Consortium and German Cancer Research Center Heidelberg Germany

Department of Urology University of Eastern Piedmont Maggiore della Carità Hospital Novara Italy

International Kidney Cancer Coalition Duivendrecht The Netherlands

The Royal Free London NHS Foundation Trust London UK; UCL Division of Surgery and Interventional Science London UK; Department of Urology The Netherlands Cancer Institute Antoni van Leeuwenhoek Hospital Amsterdam The Netherlands

The Royal Free NHS Trust and Barts Cancer Institute Queen Mary University of London London UK

Unit of Urological Robotic Surgery and Renal Transplantation University of Florence Careggi Hospital Florence Italy; Department of Experimental and Clinical Medicine University of Florence Florence Italy; European Association of Urology Young Academic Urologists Renal Cancer Working Group Arnhem The Netherlands

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