Predictive factors of multiple sclerosis relapse after the first demyelinating event: A 5-year follow-up
Language English Country Netherlands Media print-electronic
Document type Letter
PubMed
36805172
DOI
10.1016/j.msard.2023.104566
PII: S2211-0348(23)00070-6
Knihovny.cz E-resources
- Keywords
- Clinically isolated syndrome, Demyelinating diseases, Magnetic resonance imaging, Multiple sclerosis, Oligoclonal bands,
- MeSH
- Chronic Disease MeSH
- Demyelinating Diseases * diagnosis pathology MeSH
- Humans MeSH
- Magnetic Resonance Imaging MeSH
- Follow-Up Studies MeSH
- Spinal Cord Diseases * MeSH
- Oligoclonal Bands MeSH
- Multiple Sclerosis * diagnosis epidemiology therapy MeSH
- Check Tag
- Humans MeSH
- Publication type
- Letter MeSH
- Names of Substances
- Oligoclonal Bands MeSH
There is a growing need to discover the characteristics that predict prognostic factors after the first demyelinating event. In this study of 141 patients that met the 2017 McDonald criteria, a higher number of oligoclonal bands, cervical spinal cord demyelinating lesions, and sensory involvement were identified as independent predictors of the second demyelinating event during the 5-year follow-up period in patients who experienced the first demyelinating event. The identification of the aforementioned risk variables will make it possible to identify patients who are more likely to exhibit early second demyelinating event, implying more frequent monitoring and consideration of early application of highly effective disease-modifying treatment.
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