The Reduction of the Cell Nuclear Size in the Cell Body Space During the Differentiation Might Be Cell Lineage Specific (A Retrospective Morphological Note)
Language English Country Czech Republic Media print
Document type Journal Article
PubMed
37795894
PubMed Central
PMC10634560
DOI
10.33549/physiolres.935039
PII: 935039
Knihovny.cz E-resources
- MeSH
- Cell Differentiation MeSH
- Cell Lineage MeSH
- Leukemia, Lymphocytic, Chronic, B-Cell * MeSH
- Humans MeSH
- Retrospective Studies MeSH
- Cell Body * MeSH
- Cell Nucleus Size MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
The cell body space occupied by the nucleus decreased during the cell differentiation of the granulocytic cell lineage in CML (Chronic Myeloid Leukemia) patients. In contrary, in patients suffering from CLL (Chronic Lymphocytic Leukemia), the cell body space occupied by the nucleus during the cell differentiation of the lymphocytic lineage did not decrease despite the reduction of the cell size. Thus, the cell body space occupied by the cell nucleus during the differentiation was characteristic for each of these cell lineages.
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