Radioguidance that makes use of β-emitting radionuclides is gaining in popularity and could have potential to strengthen the range of existing radioguidance techniques. While there is a strong tendency to develop new PET radiotracers, due to favorable imaging characteristics and the success of theranostics research, there are practical challenges that need to be overcome when considering use of β-emitters for surgical radioguidance. In this position paper, the EANM identifies the possibilities and challenges that relate to the successful implementation of β-emitters in surgical guidance, covering aspects related to instrumentation, radiation protection, and modes of implementation.

Computer Aided Medical Procedures and Augmented Reality Institute of Informatics I16 Technical University of Munich Munich Germany

Department of Clinical Physiology Nuclear Medicine and PET Rigshospitalet University Hospital Copenhagen Copenhagen Denmark

Department of Medical Physics Motol University Hospital Prague Czech Republic

Department of Medical Physics Ospedale U Parini Aosta Italy

Department of Nuclear Medicine Inselspital Bern University Hospital University of Bern Bern Switzerland

Department of Nuclear Medicine Medizinische Hochschule Hannover Hannover Germany

Department of Nuclear Medicine University Hospital Essen West German Cancer Center University of Duisburg Essen Essen Germany

Department of Radiology Memorial Sloan Kettering Cancer Center New York NY USA

Institute of Nuclear Medicine University College London Hospital Tower 5 235 Euston Road London NW1 2BU UK

Interventional Molecular Imaging Laboratory Department of Radiology Leiden University Medical Center Leiden the Netherlands

Molecular Pharmacology Program Memorial Sloan Kettering Cancer Center New York NY USA

Nuclear Medicine Department Hospital Clinic Barcelona Barcelona Spain

Royal Free London NHS Foundation Trust Hospital London UK

UMR 1101 LaTIM INSERM University of Brest Brest France

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