Leukodystrophy, Metachromatic [metachromatická leukodystrofie]

topical
29
Terms

deficit arylsulfatázy A
deficit cerebrosidsulfatázy
Greenfieldova nemoc
leukodystrofie metachromatická
metachromatická leukodystrofie adultní forma
metachromatická leukodystrofie juvenilní
metachromatická leukodystrofie pozdní infantilní

 

ARSA Deficiency
Arylsulfatase A Deficiency
Arylsulfatase A Deficiency Disease
Cerebral sclerosis, Diffuse, Metachromatic Form
Cerebroside Sulfatase Deficiency
Cerebroside Sulphatase Deficiency Disease
Greenfield Disease
Greenfield's Disease
Leukodystrophy, Metachromatic, Adult
Leukodystrophy, Metachromatic, Juvenile
Metachromatic Leukodystrophy
Metachromatic Leukodystrophy, Adult
Metachromatic Leukodystrophy, Adult-Type
Metachromatic Leukodystrophy, Infant
Metachromatic Leukodystrophy, Infant-Type
Metachromatic Leukodystrophy, Juvenile
Metachromatic Leukodystrophy, Juvenile-Type
Metachromatic Leukodystrophy, Late Infantile
Metachromatic Leukoencephalopathy
Sulfatide Lipidosis

Persistent link   https://www.medvik.cz/link/D007966
Definition

An autosomal recessive metabolic disease caused by a deficiency of CEREBROSIDE-SULFATASE leading to intralysosomal accumulation of cerebroside sulfate (SULFOGLYCOSPHINGOLIPIDS) in the nervous system and other organs. Pathological features include diffuse demyelination, and metachromatically-staining granules in many cell types such as the GLIAL CELLS. There are several allelic and nonallelic forms with a variety of neurological symptoms.

DUI
D007966 MeSH Browser
CUI
M0012416
History note
1974
Public note
1974

C Diseases
C10.228.140 Brain Diseases 1 178
C10.228.140.163 Brain Diseases, Metabolic 84
C10.228.140.163.100.362.250 Adrenoleukodystrophy 41
C10.228.140.163.100.362.312 Alexander Disease 6
C10.228.140.163.100.362.375 Canavan Disease 9
C10.228.140.163.100.362.500 Leukodystrophy, Globoid Cell 16
C10.228.140.163.100.362.550 Leukodystrophy, Metachromatic 29
C10.228.140.163.100.362.775 Pelizaeus-Merzbacher Disease 11
C10.228.140.163.100.435.825 Sphingolipidoses 12
C10.228.140.163.100.435.825.850 Sulfatidosis 1
C10.228.140.163.100.435.825.850.500 Leukodystrophy, Metachromatic 29
C10.228.140.163.100.435.825.850.750 Multiple Sulfatase Deficiency Disease
C10.228.140.695 Leukoencephalopathies 11
C10.228.140.695.625.250 Adrenoleukodystrophy 41
C10.228.140.695.625.312 Alexander Disease 6
C10.228.140.695.625.375 Canavan Disease 9
C10.228.140.695.625.500 Leukodystrophy, Globoid Cell 16
C10.228.140.695.625.550 Leukodystrophy, Metachromatic 29
C10.228.140.695.625.775 Pelizaeus-Merzbacher Disease 11
C10.314.400.250 Adrenoleukodystrophy 41
C10.314.400.312 Alexander Disease 6
C10.314.400.375 Canavan Disease 9
C16.320.565.189.362.250 Adrenoleukodystrophy 41
C16.320.565.189.362.312 Alexander Disease 6
C16.320.565.189.362.375 Canavan Disease 9
C16.320.565.189.362.500 Leukodystrophy, Globoid Cell 16
C16.320.565.189.362.550 Leukodystrophy, Metachromatic 29
C16.320.565.189.362.775 Pelizaeus-Merzbacher Disease 11
C16.320.565.189.435.825 Sphingolipidoses 12
C16.320.565.189.435.825.850 Sulfatidosis 1
C16.320.565.189.435.825.850.500 Leukodystrophy, Metachromatic 29
C16.320.565.189.435.825.850.750 Multiple Sulfatase Deficiency Disease
C16.320.565.398.641 Lipidoses 35
C16.320.565.398.641.803 Sphingolipidoses 12
C16.320.565.398.641.803.925 Sulfatidosis 1
C16.320.565.398.641.803.925.500 Leukodystrophy, Metachromatic 29
C16.320.565.398.641.803.925.750 Multiple Sulfatase Deficiency Disease
C16.320.565.595 Lysosomal Storage Diseases 72
C16.320.565.595.554.825 Sphingolipidoses 12
C16.320.565.595.554.825.850 Sulfatidosis 1
C16.320.565.595.554.825.850.500 Leukodystrophy, Metachromatic 29
C16.320.565.595.554.825.850.750 Multiple Sulfatase Deficiency Disease
C18.452 Metabolic Diseases 1 196
C18.452.132.100.362.250 Adrenoleukodystrophy 41
C18.452.132.100.362.312 Alexander Disease 6
C18.452.132.100.362.375 Canavan Disease 9
C18.452.132.100.362.500 Leukodystrophy, Globoid Cell 16
C18.452.132.100.362.550 Leukodystrophy, Metachromatic 29
C18.452.132.100.362.775 Pelizaeus-Merzbacher Disease 11
C18.452.132.100.435.825 Sphingolipidoses 12
C18.452.132.100.435.825.850 Sulfatidosis 1
C18.452.132.100.435.825.850.500 Leukodystrophy, Metachromatic 29
C18.452.132.100.435.825.850.750 Multiple Sulfatase Deficiency Disease
C18.452.584.563.641 Lipidoses 35
C18.452.584.563.641.803 Sphingolipidoses 12
C18.452.584.563.641.803.925 Sulfatidosis 1
C18.452.584.563.641.803.925.500 Leukodystrophy, Metachromatic 29
C18.452.584.563.641.803.925.750 Multiple Sulfatase Deficiency Disease
C18.452.648.189.362.250 Adrenoleukodystrophy 41
C18.452.648.189.362.312 Alexander Disease 6
C18.452.648.189.362.375 Canavan Disease 9
C18.452.648.189.362.500 Leukodystrophy, Globoid Cell 16
C18.452.648.189.362.550 Leukodystrophy, Metachromatic 29
C18.452.648.189.362.775 Pelizaeus-Merzbacher Disease 11
C18.452.648.189.435.825 Sphingolipidoses 12
C18.452.648.189.435.825.850 Sulfatidosis 1
C18.452.648.189.435.825.850.500 Leukodystrophy, Metachromatic 29
C18.452.648.189.435.825.850.750 Multiple Sulfatase Deficiency Disease
C18.452.648.398.641 Lipidoses 35
C18.452.648.398.641.803 Sphingolipidoses 12
C18.452.648.398.641.803.925 Sulfatidosis 1
C18.452.648.398.641.803.925.500 Leukodystrophy, Metachromatic 29
C18.452.648.398.641.803.925.750 Multiple Sulfatase Deficiency Disease
C18.452.648.595 Lysosomal Storage Diseases 72
C18.452.648.595.554.825 Sphingolipidoses 12
C18.452.648.595.554.825.850 Sulfatidosis 1
C18.452.648.595.554.825.850.500 Leukodystrophy, Metachromatic 29
C18.452.648.595.554.825.850.750 Multiple Sulfatase Deficiency Disease

Cerebral Sclerosis, Diffuse, Scholz Type Disease MeSH Browser

Combined Saposin Deficiency Disease MeSH Browser

Metachromatic Leukodystrophy due to Saposin B Deficiency Disease MeSH Browser

Metachromatic Leukodystrophy, Adult-Onset, with Normal Arylsulfatase A Disease MeSH Browser

Pseudoarylsulfatase A Deficiency Disease MeSH Browser