Surgical Treatment of Paediatric Thalamic Gliomas-Single-Centre Experience
Status PubMed-not-MEDLINE Jazyk angličtina Země Švýcarsko Médium electronic
Typ dokumentu časopisecké články
PubMed
38391716
PubMed Central
PMC10886717
DOI
10.3390/brainsci14020141
PII: brainsci14020141
Knihovny.cz E-zdroje
- Klíčová slova
- bithalamic gliomas, paediatric thalamic gliomas, radical surgery of gliomas in children,
- Publikační typ
- časopisecké články MeSH
The surgical treatment of paediatric thalamic gliomas has been burdened with high morbidity, and these lesions were often considered inoperable. With new approaches and intraoperative technologies, we can remove tumours once deemed inoperable. In our single centre, we have operated on 11 paediatric patients over the course of 8 years. We have performed eight GTR resections and three intended subtotal resections. The postoperative neurological deficit ranged from mild to very severe for motor weakness and none to severe for aphasia after surgery, with all of the patients improving at 3-month follow-up. Radicality in the surgical approach to thalamic gliomas in children has shown significant benefits when compared to more conservative approaches. For children with LGGs, extensive surgical resection is associated with improved prognosis and longer progression-free survival. However, it does not yield the same proportional benefit for HGGs due to its aggressive nature and worse outlook.
Department of Neurosurgery University Hospital Olomouc 77900 Olomouc Czech Republic
Department of Paediatric Neurology University Hospital Ostrava 70852 Ostrava Czech Republic
Department of Paediatric Oncology University Hospital Brno 66263 Brno Czech Republic
Department of Paediatrics University Hospital Olomouc 77900 Olomouc Czech Republic
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