Oedema disease of weaned piglets is caused by shigatoxigenic Escherichia coli (STEC), typically harbouring the stx2e gene and F18 adhesins. The aim of this study was to assess the effect of a commercially available oedema disease vaccine on the zootechnical performance, mortality and individual antibiotic treatment in a herd, in which non-typical STEC strains without F18 adhesin have been identified. The zootechnical performance (average daily gain, total weight gain), mortality and individual antibiotic treatment were compared between vaccinated and non-vaccinated control piglets in a monocentric field efficacy study, which was performed using two groups in a parallel, randomised design. A significantly higher average daily gain and total weight gain were recorded in the vaccinated piglets in comparison to the controls. The lower morbidity, mortality and antibiotic treatment in piglets in the vaccine group were not statistically significant. As a conclusion, the positive effect of the vaccination was confirmed in the herd with prevalent STEC not harbouring F18 adhesin. The vaccine was, therefore, also effective against oedema disease caused by such unusual STEC isolates, under the conditions of this study.

Ceva Sante Animale France Libourne France

Department of Experimental Biology Faculty of Science Masaryk University Brno Brno Czech Republic

Swine and Ruminant Clinic Faculty of Veterinary Medicine University of Veterinary Sciences Brno Brno Czech Republic

Veterinary Research Institute Brno Czech Republic

ZOD Zichlinek Zichlinek Czech Republic

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Shiga Toxin, Stx2e, Influences the Activity of Porcine Lymphocytes In Vitro