Dental pulp stem cells - A basic research and future application in regenerative medicine
Jazyk angličtina Země Francie Médium print-electronic
Typ dokumentu časopisecké články, přehledy
PubMed
39024839
DOI
10.1016/j.biopha.2024.116990
PII: S0753-3322(24)00874-6
Knihovny.cz E-zdroje
- Klíčová slova
- Dental pulp, Non-coding RNAs, Signaling pathways, Stem cells,
- MeSH
- buněčná diferenciace MeSH
- kmenové buňky * cytologie metabolismus MeSH
- lidé MeSH
- nekódující RNA genetika MeSH
- regenerativní lékařství * metody MeSH
- transplantace kmenových buněk metody MeSH
- zubní dřeň * cytologie MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
- Názvy látek
- nekódující RNA MeSH
Dental pulp is a valuable and accessible source of stem cells (DPSCs) with characteristics similar to mesenchymal stem cells. DPSCs can regenerate a range of tissues and their potential for clinical application in regenerative medicine is promising. DPSCs have been found to express low levels of Class II HLA-DR (MHC) molecules, making them potential candidates for allogeneic transplantation without matching the donor's tissue. Research on the correlation between non-coding RNAs (ncRNAs) and human dental pulp stem cells (DPSCs) provides promising insights into the use of these cells in clinical settings for a wide range of medical conditions. It is possible to use a number of ncRNAs in order to restore the functional role of downregulated ncRNAs that are correlated with osteoblastogenesis, or to suppress the functional role of overexpressed ncRNAs associated with osteoclast differentiation in some cases.
Atherosclerosis Research Center Ahvaz Jundishapur University of Medical Sciences Ahvaz Iran
Cellivia 3 S A Poznan 60 529 Poland
Prestage Department of Poultry Sciences North Carolina State University Raleigh NC 27695 USA
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