Dental pulp stem cells - A basic research and future application in regenerative medicine

. 2024 Sep ; 178 () : 116990. [epub] 20240717

Jazyk angličtina Země Francie Médium print-electronic

Typ dokumentu časopisecké články, přehledy

Perzistentní odkaz   https://www.medvik.cz/link/pmid39024839
Odkazy

PubMed 39024839
DOI 10.1016/j.biopha.2024.116990
PII: S0753-3322(24)00874-6
Knihovny.cz E-zdroje

Dental pulp is a valuable and accessible source of stem cells (DPSCs) with characteristics similar to mesenchymal stem cells. DPSCs can regenerate a range of tissues and their potential for clinical application in regenerative medicine is promising. DPSCs have been found to express low levels of Class II HLA-DR (MHC) molecules, making them potential candidates for allogeneic transplantation without matching the donor's tissue. Research on the correlation between non-coding RNAs (ncRNAs) and human dental pulp stem cells (DPSCs) provides promising insights into the use of these cells in clinical settings for a wide range of medical conditions. It is possible to use a number of ncRNAs in order to restore the functional role of downregulated ncRNAs that are correlated with osteoblastogenesis, or to suppress the functional role of overexpressed ncRNAs associated with osteoclast differentiation in some cases.

Atherosclerosis Research Center Ahvaz Jundishapur University of Medical Sciences Ahvaz Iran

Cellivia 3 S A Poznan 60 529 Poland

Cellivia 3 S A Poznan 60 529 Poland; Department of Histology and Embryology Poznan University of Medical Sciences Poznan 60 781 Poland

Centre for Craniofacial and Regenerative Biology Dental Institute King's College London London WC2R 2LS UK

Department of Diagnostics and Clinical Sciences Institute of Veterinary Medicine Nicolaus Copernicus University in Torun Torun 87 100 Poland

Department of Diagnostics Poznan University of Medical Sciences Bukowska 70 Poznań 60 812 Poland; Department of Maxillofacial Surgery Poznan University of Medical Sciences Przybyszewskiego 49 Poznań 60 355 Poland

Department of Veterinary Surgery Institute of Veterinary Medicine Nicolaus Copernicus University in Torun Torun 87 100 Poland

Department of Veterinary Surgery Institute of Veterinary Medicine Nicolaus Copernicus University in Torun Torun 87 100 Poland; Division of Anatomy Department of Human Morphology and Embryology Faculty of Medicine Wroclaw Medical University Wroclaw 50 368 Poland; College of Agriculture and Life Sciences North Carolina State University Raleigh NC 27695 USA; Center of Assisted Reproduction Department of Obstetrics and Gynecology University Hospital and Masaryk University Brno Czech Republic

Division of Anatomy Department of Human Morphology and Embryology Faculty of Medicine Wroclaw Medical University Wroclaw 50 368 Poland

Division of Histology and Embryology Department of Human Morphology and Embryology Faculty of Medicine Wroclaw Medical University Wroclaw 50 368 Poland

Division of Histology and Embryology Department of Human Morphology and Embryology Faculty of Medicine Wroclaw Medical University Wroclaw 50 368 Poland; Division of Anatomy and Histology University of Zielona Góra Zielona Góra 65 046 Poland

Division of Ultrastructural Research Department of Human Morphology and Embryology Wroclaw Medical University Wroclaw 50 368 Poland

Fertility Infertility and Perinatology Research Center Ahvaz Jundishapur University of Medical Sciences Ahvaz Iran

Prestage Department of Poultry Sciences North Carolina State University Raleigh NC 27695 USA

WSPL SP ZOZ; ul Szylinga 1 Poznań Poland

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