Musca domestica L., a common housefly, and Culex quinquefasciatus mosquito are quite well-known pests that can transfer a wide range of diseases to humans as well as animals. In this study, various isoborneol derivatives including esters, ethers, and thioethers were synthesized from isoborneol under mild conditions. These derivatives were evaluated for inhibition of house-fly M. domestica adults and Cx. quinquefasciatus larvae. Two of the synthesized isoborneol ester derivatives (2 and 3) showed good activity against both insect species. Additional two derivatives (6 and 9) were active against M. domestica L., and the derivatives (1-3, 8) were active against Cx. quinquefasciatus larvae.

Crop Research Institute Drnovska 507 161 06 Prague 6 Ruzyne Czech Republic

Department of Plant Protection Czech University of Life Sciences Prague Kamycka 129 165 00 Prague 6 Suchdol Czech Republic

K J Somaiya College of Science and Commerce Vidyavihar Mumbai 400086 Maharashtra India

Laboratory for Advanced Research in Natural and Synthetic Chemistry KET's 5 G Vaze College Mithagar Road Mulund Mumbai 400081 Maharashtra India

Environ Sci Pollut Res Int. 2024 Oct;31(47):58200. doi: 10.1007/s11356-024-35130-8. PubMed

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