Daprodustat: a new approach to the treatment of anemia in chronic kidney disease
Language English Country Czech Republic Media print
Document type Journal Article, Review
PubMed
40035302
DOI
10.36290/csf.2024.013
PII: 139784
Knihovny.cz E-resources
- Keywords
- chronic kidney disease., daprodustat, hypoxia-inducible factor prolyl hydroxylase inhibitors,
- MeSH
- Anemia * drug therapy etiology MeSH
- Barbiturates * therapeutic use MeSH
- Renal Insufficiency, Chronic * complications MeSH
- Glycine * analogs & derivatives therapeutic use pharmacology MeSH
- Prolyl-Hydroxylase Inhibitors * therapeutic use MeSH
- Humans MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
- Names of Substances
- Barbiturates * MeSH
- Glycine * MeSH
- GSK1278863 MeSH Browser
- Prolyl-Hydroxylase Inhibitors * MeSH
Daprodustat: a new approach to the treatment of anemia in chronic kidney disease Daprodustat, also known under the trade name DUVROQ, is a small molecule developed by GlaxoSmithKline, which has become a promising drug in the field of anemia treatment in patients with chronic kidney disease. Daprodustat belongs to a group of drugs called hypoxia-inducible factor prolyl hydroxylase inhibitors. These drugs interfere with the regulation of erythropoietin, which is a key factor in the production of red blood cells. This drug was approved in Japan in June 2020 and clinical studies with it are ongoing in several countries around the world, where they focus on evaluating the effectiveness and safety in various populations of patients with chronic kidney disease.
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