Pediatric cardiac arrest registries and survival outcomes: A European study
Status PubMed-not-MEDLINE Jazyk angličtina Země Nizozemsko Médium electronic-ecollection
Typ dokumentu časopisecké články
PubMed
40046495
PubMed Central
PMC11880730
DOI
10.1016/j.resplu.2025.100902
PII: S2666-5204(25)00039-6
Knihovny.cz E-zdroje
- Klíčová slova
- Cardiac arrest registries, Epidemiology, Outcomes, Pediatric cardiac arrest,
- Publikační typ
- časopisecké články MeSH
OBJECTIVE: The epidemiology of pediatric cardiac arrest in Europe is largely unknown. We aimed to characterize pediatric cardiac arrest registries and obtain the first survival outcome data on pediatric cardiac arrest in Europe. DESIGN: This is a prospective multinational survey. SETTING: We surveyed all 53 countries in Europe asking about: the existence registries for pediatric out-of-hospital cardiac arrest (pOHCA) and/or in-hospital cardiac arrest (pIHCA)), the data collected, and the structure of the registries. Subsequently, we investigated outcomes (number of pOHCA/pIHCA since start of the registry, return of spontaneous circulation (ROSC), survival to hospital discharge/30-day survival) from the countries with active registries. PATIENTS AND INTERVENTIONS: We obtained information from 33 countries including 25 of the 27 European Union states. MEASUREMENTS AND MAIN RESULTS: Thirteen countries (39%) have an ongoing pediatric cardiac arrest registry (pOHCA: 11 countries, pIHCA: 8 countries). All use the Utstein template for data collection. Five countries (15%) collect data about CPR quality. Eleven countries (33%) expressed interest in European collaboration on registry data. Overall, 13 countries reported data on outcomes from a total of 17,708 pOHCAs and 2,743 pIHCAs. The ROSC rate after pOHCA ranges from 10% to 72% as compared to 60% to 72% after pIHCA. Survival to hospital discharge ranges from 16% to 39% after pOHCA as compared to 32% to 57% after pIHCA. CONCLUSIONS: Less than 40% of the European countries have a pOHCA and/or pIHCA registry, reporting a wide variety in survival rates, especially after pOHCA. More systematic data collection is needed to identify the real incidence and outcomes from pediatric cardiac arrest, ideally through a joint European registry.
Department of Medicine Randers Regional Hospital Skovlyvej 15 8930 Randers Denmark
Health Research Institute of the Gregorio Marañón Hospital Madrid Spain
Heart Center Leipzig University Hospital Leipzig Strümpellstraße 39 04289 Leipzig Germany
Medical Education University Medical Center Heidelberglaan 100 3584 CX Utrecht the Netherlands
Paediatric Intensive Care Unit NH Hospital K Nemocnici 1106 14 268 01 Hořovice Czech Republic
SAMUR Protección Civil Rda de las Provincias 7 Moncloa Aravaca 28011 Madrid Spain
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Holmberg M., Andersen L., Fitzmaurice G., et al. Annual incidence of adult and pediatric in-hospital cardiac arrest in the United States. j. 2019;12(7) PubMed PMC
Atkins D.L., Everson-Stewart S., Sears G.K., et al. Epidemiology and outcomes from out-of-hospital cardiac arrest in children: the resuscitation outcomes consortium epistry-cardiac arrest. Circulation. 2009;119(11):1484–1491. doi: 10.1161/CIRCULATIONAHA.108.802678. PubMed DOI PMC
Okubo M., Chan H.K., Callaway C.W., Mann N.C., Wang H.E. Characteristics of paediatric out-of-hospital cardiac arrest in the United States. Resuscitation. 2020;153:227–233. doi: 10.1016/j.resuscitation.2020.04.023. PubMed DOI
About WHO Europe. https://www.who.int/europe/about-us/about-who-europe.
Bureau PR. 2024 world population data sheet. 2024.
del Castillo J., López-Herce J., Carrillo A., et al. Cardiac arrest and resuscitation in the pediatric intensive care unit: a prospective multicenter multinational study. Resuscitation. 2014;85(10):1380–1386. doi: 10.1016/j.resuscitation.2014.06.024. PubMed DOI
Skellett S., Orzechowska I., Thomas K., Fortune P.M. The landscape of paediatric in-hospital cardiac arrest in the United Kingdom National Cardiac Arrest Audit. Resuscitation. 2020;155 doi: 10.1016/j.resuscitation.2020.07.026. PubMed DOI
Van Zellem L., Utens E.M., Legerstee J.S., et al. Cardiac arrest in children: Long-term health status and health-related quality of life. Pediatr Crit Care Med. 2015;16(8):693–702. doi: 10.1097/PCC.0000000000000452. PubMed DOI
Coute R.A., Nathanson B.H., Demasi S., Mader T.J., Kurz M.C. Disability-adjusted life years due to pediatric out-of-hospital cardiac arrest in the United States: a CARES surveillance group study. Circ Cardiovasc Qual Outcomes. 2023;16(5) doi: 10.1161/CIRCOUTCOMES.122.009786. PubMed DOI
Hunfeld M., Dulfer K., Rietman A., et al. Longitudinal two years evaluation of neuropsychological outcome in children after out of hospital cardiac arrest. Resuscitation. 2021;167:29–37. doi: 10.1016/j.resuscitation.2021.07.043. PubMed DOI
van Zellem L., Utens E.M., Madderom M., et al. Cardiac arrest in infants, children, and adolescents: long-term emotional and behavioral functioning. Eur J Pediatr. 2016;175(7):977–986. doi: 10.1007/s00431-016-2728-4. PubMed DOI PMC
Maconochie I.K., Aickin R., Hazinski M.F., et al. Pediatric life support: 2020 international consensus on cardiopulmonary resuscitation and emergency cardiovascular care science with treatment recommendations. Circulation. 2020;142 doi: 10.1161/CIR.0000000000000894. PubMed DOI
Nallamothu B.K., Greif R., Anderson T., et al. Ten steps toward improving in-hospital cardiac arrest quality of care and outcomes. Circ Cardiovasc Qual Outcomes. 2023:793–806. doi: 10.1161/circoutcomes.123.010491. PubMed DOI PMC
Van de Voorde P., Turner N.M., Djakow J., et al. European Resuscitation Council guidelines 2021: paediatric life support. Resuscitation. 2021;161:327–387. doi: 10.1016/j.resuscitation.2021.02.015. PubMed DOI
Zaritsky A., Nadkarni V., Hazinski M.F., et al. Recommended guidelines for uniform reporting of pediatric advanced life support: the pediatric utstein style. Ann Emerg Med. 1995;26(4):487–503. doi: 10.1016/S0196-0644(95)70119-2. PubMed DOI
Topjian A.A., Scholefield B.R., Pinto N.P., et al. P-COSCA (Pediatric Core Outcome Set for Cardiac Arrest) in children: an advisory statement from the international liaison committee on resuscitation. Resuscitation. 2021 doi: 10.1016/j.resuscitation.2021.01.023. PubMed DOI
Suominen P., Olkkola K.T., Voipio V., Korpela R., Palo R., Räsänen J. Utstein style reporting of in-hospital paediatric cardiopulmonary resuscitation. Resuscitation. 2000;45(1):17–25. doi: 10.1016/S0300-9572(00)00167-2. PubMed DOI
Gräsner J.T., Lefering R., Koster R.W., et al. EuReCa ONE—27 Nations, ONE Europe, ONE Registry: a prospective one month analysis of out-of-hospital cardiac arrest outcomes in 27 countries in Europe. Resuscitation. 2016;105:188–195. doi: 10.1016/j.resuscitation.2016.06.004. PubMed DOI
Harris P.A., Taylor R., Thielke R., Payne J., Gonzalez N., Conde J.G. Research electronic data capture (REDCap)-A metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform. 2009;42(2):377–381. doi: 10.1016/j.jbi.2008.08.010. PubMed DOI PMC
Europe. https://en.wikipedia.org/wiki/Europe.
Booth A., Moylan A., Hodgson J., et al. Resuscitation registers: How many active registers are there and how many collect data on paediatric cardiac arrests? Resuscitation. 2018;129:70–75. doi: 10.1016/j.resuscitation.2018.03.029. PubMed DOI
Sinha S.S., Sukul D., Lazarus J.J., et al. Identifying important gaps in randomized controlled trials of adult cardiac arrest treatments: a systematic review of the published literature. Circ Cardiovasc Qual Outcomes. 2016;9(6):749–756. doi: 10.1161/CIRCOUTCOMES.116.002916.q. PubMed DOI PMC
Donoghue A.J., Nadkarni V., Berg R.A., et al. Out-of-hospital pediatric cardiac arrest: An epidemiologic review and assessment of current knowledge. Ann Emerg Med. 2005;46(6):512–522. doi: 10.1016/j.annemergmed.2005.05.028. PubMed DOI
Kiguchi T., Okubo M., Nishiyama C., et al. Out-of-hospital cardiac arrest across the world: first report from the International Liaison Committee on Resuscitation (ILCOR) Resuscitation. 2020;152:39–49. doi: 10.1016/j.resuscitation.2020.02.044. PubMed DOI
Fukuda T., Ohashi-Fukuda N., Kobayashi H., et al. Conventional versus compression-only versus no-bystander cardiopulmonary resuscitation for pediatric out-of-hospital cardiac arrest. Circulation. 2016;134(25):2060–2070. doi: 10.1161/CIRCULATIONAHA.116.023831. PubMed DOI
Holmberg M.J., Wiberg S., Ross C.E., et al. Trends in survival after pediatric in-hospital cardiac arrest in the United States. Circulation. 2019;140(17):1398–1408. doi: 10.1161/CIRCULATIONAHA.119.041667. PubMed DOI PMC
Seaman K.G., Anders J. Shockingly good long-term outcomes after pediatric OHCA, paired with high quality CPR can maximize pediatric survival outcomes. Resuscitation. 2021;166:137–138. doi: 10.1016/j.resuscitation.2021.06.015. PubMed DOI
Wissenberg M., Lippert F.K., Folke F., et al. Association of national initiatives to improve cardiac arrest management with rates of bystander intervention and patient survival after out-of-hospital cardiac arrest. JAMA. 2013;310(13):1377–1384. doi: 10.1001/jama.2013.278483. PubMed DOI
De Visser M., Bosch J., Bootsma M., et al. An observational study on survival rates of patients with out-of-hospital cardiac arrest in the Netherlands after improving the â chain of survival’. BMJ Open. 2019;9(7):1–8. doi: 10.1136/bmjopen-2019-029254. PubMed DOI PMC
Schroeder D.C., Semeraro F., Greif R., et al. KIDS SAVE LIVES: basic life support education for schoolchildren: a narrative review and scientific statement from the international liaison committee on resuscitation. Circulation. 2023;147(24):1854–1868. doi: 10.1161/CIR.0000000000001128. PubMed DOI
Katzenschlager S., Huck M., Brenner S., Hoffmann F., Kramer-Johansen J., Popp E. Out-of-hospital cardiac arrest in children : an epidemiological study based on the German Resuscitation Registry identifying modifiable factors for return of spontaneous circulation. BMC Crit Care. 2023:1–24. doi: 10.21203/rs.3.rs-3156608/v1. PubMed DOI PMC
Holgersen M.G., Jensen T.W., Breindahl N., et al. Pediatric out-of-hospital cardiac arrest in Denmark. Scand J Trauma Resusc Emerg Med. 2022;30(1):1–8. doi: 10.1186/s13049-022-01045-x. PubMed DOI PMC
Gravesteijn B.Y., Schluep M., Lingsma H.F., et al. Between-centre differences in care for in-hospital cardiac arrest: a prospective cohort study. Crit Care. 2021;25(1):1–12. doi: 10.1186/s13054-021-03754-8. PubMed DOI PMC
Wolfe H., Zebuhr C., Topjian A.A., et al. Interdisciplinary ICU cardiac arrest debriefing improves survival outcomes. Crit Care Med. 2014;42(7):1688–1695. doi: 10.1097/CCM.0000000000000327. PubMed DOI PMC
Dewan M., Parsons A., Tegtmeyer K., et al. Contextual factors affecting implementation of in-hospital pediatric CPR quality improvement interventions in a resuscitation collaborative. Pediatr Qual Saf. 2021;6(5):E455. doi: 10.1097/pq9.0000000000000455. PubMed DOI PMC
Lauridsen K.G., Lasa J.J., Raymond T.T., et al. Association of chest compression pause duration prior to E-CPR cannulation with cardiac arrest survival outcomes. Resuscitation. 2022;177:85–92. doi: 10.1016/j.resuscitation.2022.05.004. PubMed DOI
Sweberg T., Sen A.I., Mullan P.C., et al. Description of hot debriefings after in-hospital cardiac arrests in an international pediatric quality improvement collaborative. Resuscitation. 2018;128:181–187. doi: 10.1016/j.resuscitation.2018.05.015. PubMed DOI
Niles D.E., Duval-Arnould J., Skellett S., et al. Characterization of pediatric in-hospital cardiopulmonary resuscitation quality metrics across an international resuscitation collaborative. Pediatr Crit Care Med. 2018 doi: 10.1097/PCC.0000000000001520. PubMed DOI
Sutton R.M., Reeder R.W., Landis W., et al. Chest compression rates and pediatric in-hospital cardiac arrest survival outcomes. Resuscitation. 2018;130:159–166. doi: 10.1016/j.resuscitation.2018.07.015. PubMed DOI PMC
Fowler J.C., Morgan R.W., O’Halloran A., et al. The impact of pediatric post-cardiac arrest care on survival: a multicenter review from the AHA get with the Guidelines®-resuscitation post-cardiac arrest care registry. Resuscitation. 2024;202 doi: 10.1016/j.resuscitation.2024.110301. PubMed DOI
Bradley S.M., Huszti E., Warren S.A., Merchant R.M., Sayre M.R., Nichol G. Duration of hospital participation in get with the guidelines-resuscitation and survival of in-hospital cardiac arrest. Resuscitation. 2012;83(11):1349–1357. doi: 10.1016/j.resuscitation.2012.03.014. PubMed DOI PMC
Get with the Guidelines – Resuscitation. https://www.heart.org/en/professional/quality-improvement/get-with-the-guidelines/get-with-the-guidelines-resuscitation.