Using a Novel Pulsed Field Ablation Technique to Identify the Critical Isthmus Within a Tachycardia Circuit
Status PubMed-not-MEDLINE Language English Country United States Media electronic-ecollection
Document type Case Reports, Journal Article
PubMed
40052006
PubMed Central
PMC11882119
DOI
10.19102/icrm.2025.16023
PII: icrm.2025.16023
Knihovny.cz E-resources
- Keywords
- Atrial tachycardia, catheter ablation, novel mapping technique, pulsed field ablation, reversible electroporation,
- Publication type
- Journal Article MeSH
- Case Reports MeSH
Pulsed field ablation uses irreversible electroporation to interrupt cellular membranes and induce myocyte apoptosis. Reversible electroporation has been used in other specialties, but its utility in cardiac ablation is unknown. Here, a 69-year-old woman undergoing repeat ablation for atypical atrial flutter presented with extensive scar after cardiac surgery (including MAZE) and previous ablation, leading to a macro re-entry circuit. To minimize superfluous lesions and further arrhythmia, we used a single pulse confirming the isthmus location, with cessation of the arrhythmia. As a conclusion, reversible electroporation may be used to test areas of interest prior to irreversible lesion creation.
Cardiology Department Midlands Regional Hospital Mullingar Mullingar Westmeath Ireland
Electrophysiology Department Beacon Hospital Sandyford Dublin Ireland
Medtronic Ireland Dublin Ireland
School of Medicine University College Dublin Belfield Dublin Ireland
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