BACKGROUND: Penile cancer patients with advanced metastatic disease in the inguinal region present a therapeutic challenge. This study assesses the long-term viability of tensor fascia lata (TFL) flap for inguinal reconstruction after inguinal lymphadenectomy in metastatic penile cancer patients. MATERIAL AND METHODS: We herein report eight cases of advanced penile cancer utilizing a TFL flap for reconstructing defects in the inguinal region. Demographic characteristics, perioperative findings and outcome of the patients were evaluated. RESULTS: Patients were followed up for 1-35 months. The mean age of patients included in this study was 58.75 years. Six out of eight patients had a favorable prognosis. The strong vascularity of the TFL flap enables excellent coverage, which can reduce the rate of ischemia and necrosis of the flap. No serious complications occurred in all cases during the perioperative period. One patient developed partial flap necrosis, which required debridement, whereas one patient underwent distal wound dehiscence which resolved with routine wound care. CONCLUSIONS: Our experience demonstrates the versatility and effectiveness of the TFL flap in addressing reconstruction of defects following inguinal lymph node dissection among patients with advanced penile cancer.

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