Adipose derived stem cells - Sources, differentiation capacity and a new target for reconstructive and regenerative medicine
Language English Country France Media print-electronic
Document type Journal Article, Review
PubMed
40194335
DOI
10.1016/j.biopha.2025.118036
PII: S0753-3322(25)00230-6
Knihovny.cz E-resources
- Keywords
- Adipocytes, Adipose-derived stem cells, Mesenchymal stem cells, Regenerative medicine,
- MeSH
- Cell Differentiation * physiology MeSH
- Stem Cells * cytology MeSH
- Humans MeSH
- Mesenchymal Stem Cells * cytology physiology MeSH
- Regenerative Medicine * methods MeSH
- Tissue Engineering methods MeSH
- Adipose Tissue * cytology MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
Adipose-derived stem cells (ADSCs) are mesenchymal stem cells (MSCs) derived from adipose tissue with mesenchymal lineage differentiation potential and remarkable potential in regenerative medicine. ADSCs are easily sourced from adipose tissue, share regenerative characteristics akin to other MSCs. Their convenient adherence to plastic culture flasks, coupled with their capacity for in vitro expansion and multi-lineage differentiation, underscores their promise as a robust tool for tissue repair and enhancement. The accessibility of human adipose tissue and the development of minimally invasive isolation protocols have further propelled the autologous use of ADSCs, fueling excitement in both organ repair and regenerative medicine. Consequently, research in ADSCsis experiencing rapid growth. A detailed overview of the current landscape of ADSCs isolation and differentiation capacity including the latest advancements in ADSCs usage, encompassing ongoing clinical investigations are important considerations to understand their potential to shape the landscape of regenerative medicine.
Atherosclerosis Research Center Ahvaz Jundishapur University of Medical Sciences Ahvaz Iran
Department of Paediatric Dentistry Poznan University of Medical Sciences Poznań Poland
Department of Pediatric Orthopedics and Musculosceletal Oncology Pomeranian Medical University
Graduate Physiology Program North Carolina State University Raleigh NC 27695 USA
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