Restored phagocytic ability of RPE patches derived from gene-corrected retinitis pigmentosa-hiPSCs on a biodegradable scaffold via clinical-grade protocol: Implications for autologous therapy

. 2025 Nov ; 12 (6) : 101609. [epub] 20250322

Status PubMed-not-MEDLINE Jazyk angličtina Země Nizozemsko Médium electronic-ecollection

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/pmid40808876
Odkazy

PubMed 40808876
PubMed Central PMC12343362
DOI 10.1016/j.gendis.2025.101609
PII: S2352-3042(25)00098-4
Knihovny.cz E-zdroje

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Lukovic D., Artero Castro A., Delgado A.B., et al. Human iPSC derived disease model of MERTK-associated retinitis pigmentosa. Sci Rep. 2015;5 PubMed PMC

Artero Castro A., Long K., Bassett A., et al. Generation of gene-corrected human induced pluripotent stem cell lines derived from retinitis pigmentosa patient with Ser331Cysfs∗5 mutation in MERTK. Stem Cell Res. 2019;34 PubMed

Sharma R., Bose D., Montford J., Ortolan D., Bharti K. Triphasic developmentally guided protocol to generate retinal pigment epithelium from induced pluripotent stem cells. STAR Protoc. 2022;3(3) PubMed PMC

Lytvynchuk L., Ebbert A., Studenovska H., et al. Subretinal implantation of human primary RPE cells cultured on nanofibrous membranes in minipigs. Biomedicines. 2022;10(3):669. PubMed PMC

Artero-Castro A., Long K., Bassett A., et al. Gene correction recovers phagocytosis in retinal pigment epithelium derived from retinitis pigmentosa-human-induced pluripotent stem cells. Int J Mol Sci. 2021;22(4):2092. PubMed PMC

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