Alarmins [alarminy]
topical
20
- Terms
-
Alarmin
Alarmin Proteins
Damage-Associated Molecular Pattern Molecules
Danger-Associated Molecular Pattern Molecules
Persistent link
https://www.medvik.cz/link/D000067531
Definition
A structurally diverse group of endogenous molecules that are multifunctional, having physiological functions inside the cell, but when released from dying cells or from cells under stress or certain immune cells, they function to activate INNATE IMMUNITY. Uncontrolled and excessive release of alarmins may contribute to INFLAMMATION; CARCINOGENESIS, and NEOPLASM METASTASIS. Alarmins are also critical for heart and nerve tissue homeostasis.
- DUI
- D000067531 MeSH Browser
- CUI
- M000599994
- Previous indexing
- HMGB1 Protein (2004-2015)
- History note
- 2016
- Public note
- 2016
Allowable subheadings
- AD
- administration & dosage 0
- AE
- adverse effects 0
- AG
- agonists 0
- AN
- analysis 1
- AI
- antagonists & inhibitors 1
- BI
- biosynthesis 0
- BL
- blood 5
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 0
- CL
- classification 1
- DF
- deficiency 0
- DE
- drug effects 1
- EC
- economics 0
- GE
- genetics 1
- HI
- history 0
- IM
- immunology 5
- IP
- isolation & purification 0
- ME
- metabolism 3
- PK
- pharmacokinetics 0
- PD
- pharmacology 0
- PH
- physiology 4
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 0
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0
...
Occurrences in Medvik records
D
Chemicals and Drugs