alarminy [Alarmins]

tematický
20
Termíny

Alarmin
Alarmin Proteins
Damage-Associated Molecular Pattern Molecules
Danger-Associated Molecular Pattern Molecules

Perzistentní odkaz   https://www.medvik.cz/link/D000067531
Definice

A structurally diverse group of endogenous molecules that are multifunctional, having physiological functions inside the cell, but when released from dying cells or from cells under stress or certain immune cells, they function to activate INNATE IMMUNITY. Uncontrolled and excessive release of alarmins may contribute to INFLAMMATION; CARCINOGENESIS, and NEOPLASM METASTASIS. Alarmins are also critical for heart and nerve tissue homeostasis.

DUI
D000067531 MeSH Prohlížeč
CUI
M000599994
Předchozí užití
HMGB1 Protein (2004-2015)
Historická pozn.
2016
Veřejná pozn.
2016