Imatinib Mesylate [imatinib mesylát]

topical
127
Terms

Glivec
imatinib

 

Alpha-(4-methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-p-tolu-p-toluidide
CGP 57148
CGP-57148
CGP57148B
Gleevec
Glivec
Imatinib
Imatinib Methanesulfonate
ST 1571
ST1571
STI 571
STI-571
STI571

Persistent link   https://www.medvik.cz/link/D000068877
Definition

A tyrosine kinase inhibitor and ANTINEOPLASTIC AGENT that inhibits the BCR-ABL kinase created by chromosome rearrangements in CHRONIC MYELOID LEUKEMIA and ACUTE LYMPHOBLASTIC LEUKEMIA, as well as PDG-derived tyrosine kinases that are overexpressed in gastrointestinal stromal tumors.

DUI
D000068877 MeSH Browser
CUI
M0391958
History note
2016 (1996)
Public note
2016; IMATINIB MESYLATE was indexed under BENZAMIDES, PIPERAZINES, and PYRIMIDINES 1996-2015

Allowable subheadings

AD
administration & dosage 27
AE
adverse effects 24
AG
agonists
AA
analogs & derivatives 1
AN
analysis
AI
antagonists & inhibitors
BL
blood 5
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry 1
CL
classification
EC
economics 2
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism 1
PK
pharmacokinetics 2
PD
pharmacology 29
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use 78
TO
toxicity 1
UR
urine 1

D Chemicals and Drugs
D02 Organic Chemicals 391
D02.065 Amides 260
D02.065.277 Benzamides 209
D02.065.277.034 Amisulpride 18
D02.065.277.051 Axitinib 70
D02.065.277.067 Bezafibrate 16
D02.065.277.135 Cisapride 33
D02.065.277.194 DEET 10
D02.065.277.225 Dinitolmide
D02.065.277.431 Hippurates 81
D02.065.277.456 Imatinib Mesylate 127
D02.065.277.480 Indoramin
D02.065.277.573 Metoclopramide 51
D02.065.277.600 Moclobemide 23
D02.065.277.650 Procainamide 20
D02.065.277.727 Procarbazine 26
D02.065.277.761 Raclopride 1
D02.065.277.796 Remoxipride
D02.065.277.866 Sulpiride 55
D02.241 Carboxylic Acids 244
D02.241.223 Acids, Carbocyclic 4
D02.241.223.100 Benzoates 212
D02.241.223.100.100 Benzamides 209
D02.241.223.100.100.033 Acecainide 2
D02.241.223.100.100.100 Aminohippuric Acids 10
D02.241.223.100.100.110 Amisulpride 18
D02.241.223.100.100.115 Axitinib 70
D02.241.223.100.100.120 Bezafibrate 16
D02.241.223.100.100.135 Cisapride 33
D02.241.223.100.100.230 DEET 10
D02.241.223.100.100.240 Dinitolmide
D02.241.223.100.100.400 Hippurates 81
D02.241.223.100.100.435 Imatinib Mesylate 127
D02.241.223.100.100.470 Indoramin
D02.241.223.100.100.510 Metoclopramide 51
D02.241.223.100.100.600 Moclobemide 23
D02.241.223.100.100.650 Procainamide 20
D02.241.223.100.100.655 Procarbazine 26
D02.241.223.100.100.761 Raclopride 1
D02.241.223.100.100.796 Remoxipride
D02.241.223.100.100.866 Sulpiride 55
D02.241.223.100.100.933 Tiapride Hydrochloride
D02.455 Hydrocarbons 139
D02.455.426 Hydrocarbons, Cyclic 24
D02.455.426.559 Hydrocarbons, Aromatic 50
D02.455.426.559.389 Benzene Derivatives 73
D02.455.426.559.389.127 Benzoates 212
D02.455.426.559.389.127.085 Benzamides 209
D02.455.426.559.389.127.085.033 Acecainide 2
D02.455.426.559.389.127.085.067 Aminohippuric Acids 10
D02.455.426.559.389.127.085.084 Amisulpride 18
D02.455.426.559.389.127.085.093 Axitinib 70
D02.455.426.559.389.127.085.101 Bezafibrate 16
D02.455.426.559.389.127.085.135 Cisapride 33
D02.455.426.559.389.127.085.230 DEET 10
D02.455.426.559.389.127.085.240 Dinitolmide
D02.455.426.559.389.127.085.460 Hippurates 81
D02.455.426.559.389.127.085.465 Imatinib Mesylate 127
D02.455.426.559.389.127.085.470 Indoramin
D02.455.426.559.389.127.085.510 Metoclopramide 51
D02.455.426.559.389.127.085.600 Moclobemide 23
D02.455.426.559.389.127.085.650 Procainamide 20
D02.455.426.559.389.127.085.655 Procarbazine 26
D02.455.426.559.389.127.085.761 Raclopride 1
D02.455.426.559.389.127.085.796 Remoxipride
D02.455.426.559.389.127.085.866 Sulpiride 55
D02.455.426.559.389.127.085.933 Tiapride Hydrochloride
D03 Heterocyclic Compounds 190
D03.383 Heterocyclic Compounds, 1-Ring 34
D03.383.606 Piperazines 740
D03.383.606.130 Almitrine 5
D03.383.606.170 Aripiprazole 51
D03.383.606.210 Buspirone 33
D03.383.606.290 Cinnarizine 17
D03.383.606.320 Cyclizine
D03.383.606.350 Delavirdine
D03.383.606.380 Diethylcarbamazine 5
D03.383.606.385 Diketopiperazines 10
D03.383.606.390 Dimethylphenylpiperazinium Iodide
D03.383.606.398 Eszopiclone 1
D03.383.606.405 Imatinib Mesylate 127
D03.383.606.450 Flunarizine 15
D03.383.606.460 Flupenthixol 15
D03.383.606.500 HEPES 2
D03.383.606.515 Hydroxyzine 15
D03.383.606.527 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine 7
D03.383.606.530 Itraconazole 106
D03.383.606.560 Ketoconazole 58
D03.383.606.596 Lidoflazine 1
D03.383.606.650 Meclizine
D03.383.606.760 Pipecuronium
D03.383.606.765 Pipemidic Acid
D03.383.606.768 Piperazine 61
D03.383.606.773 Pipobroman 2
D03.383.606.790 Piribedil
D03.383.606.800 Prasugrel Hydrochloride 54
D03.383.606.810 Prospidium
D03.383.606.827 Quipazine
D03.383.606.841 Ranolazine 5
D03.383.606.854 Sildenafil Citrate 25
D03.383.606.880 Thiethylperazine 9
D03.383.606.900 Trazodone 108
D03.383.606.920 Trimetazidine 113
D03.383.606.960 Vardenafil Dihydrochloride 23
D03.383.606.980 Vilazodone Hydrochloride 2
D03.383.606.990 Vortioxetine 13
D03.383.742 Pyrimidines 982
D03.383.742.060 Bosentan 16
D03.383.742.120 Buspirone 33
D03.383.742.148 Dasatinib 76
D03.383.742.175 Dipyridamole 149
D03.383.742.200 Epirizole
D03.383.742.279 Hexetidine 5
D03.383.742.349 Imatinib Mesylate 127
D03.383.742.418 Minoxidil 49
D03.383.742.430 Mopidamol
D03.383.742.440 Morantel
D03.383.742.470 Nicarbazin
D03.383.742.550 Oxypurinol 1
D03.383.742.592 Paliperidone Palmitate 17
D03.383.742.634 Pyrantel 2
D03.383.742.675 Pyrimethamine 58
D03.383.742.680 Pyrimidine Nucleosides 23
D03.383.742.686 Pyrimidine Nucleotides 14
D03.383.742.698 Pyrimidinones 75
D03.383.742.715 Pyrithiamine
D03.383.742.755 Rilpivirine 6
D03.383.742.775 Rosuvastatin Calcium 77
D03.383.742.795 Thiamine 135
D03.383.742.875 Trapidil
D03.383.742.906 Trimethoprim 64

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