bosentan [Bosentan]

tematický
16
Termíny

bosentan monohydrát
Stayveer

 

4-t-Butyl-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide
Bosentan Anhydrous
Bosentan Monohydrate
Ro 47-0203
Ro-47-0203
Tracleer

Perzistentní odkaz   https://www.medvik.cz/link/D000077300
Definice

Sulfonamidový a pyrimidinový derivát, který působí jako duální antagonista endotelinového receptoru používaný k léčbě plicní hypertenze a systémové sklerodermie.

A sulfonamide and pyrimidine derivative that acts as a dual endothelin receptor antagonist used to manage PULMONARY HYPERTENSION and SYSTEMIC SCLEROSIS.

DUI
D000077300 MeSH Prohlížeč
CUI
M000640413
CAS
Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)(2,2'-bipyrimidin)-4-yl)-
Historická pozn.
2019 (1994)
Veřejná pozn.
2019; BOSENTAN was indexed under SULFONAMIDES 1995-2018; and under RECEPTORS, ENDOTHELIN/antagonists 1994

Povolená podhesla

AG
agonisté 0
AA
analogy a deriváty 0
AN
analýza 0
AI
antagonisté a inhibitory 0
AD
aplikace a dávkování 1
CS
chemická syntéza 0
CH
chemie 0
HI
dějiny 0
EC
ekonomika 0
PK
farmakokinetika 0
PD
farmakologie 2
IM
imunologie 0
IP
izolace a purifikace 0
CL
klasifikace 0
BL
krev 0
ME
metabolismus 0
UR
moč 0
CF
mozkomíšní mok 0
ST
normy 0
PO
otrava 0
AE
škodlivé účinky 0
TU
terapeutické užití 1
TO
toxicita 0
RE
účinky záření 0
SD
zásobování a distribuce 0

D Chemikálie a léčiva
D02 organické látky 391
D02.065 amidy 259
D02.065.884 sulfonamidy 767
D02.065.884.060 benzensulfonamidy 2
D02.065.884.060.003 acetohexamid
D02.065.884.060.005 bosentan 16
D02.065.884.060.010 karbutamid 2
D02.065.884.060.020 celekoxib 13
D02.065.884.060.040 chlorpropamid 9
D02.065.884.060.050 chlorthalidon 41
D02.065.884.060.100 gliklazid 63
D02.065.884.060.150 mafenid 1
D02.065.884.060.160 sulfachlorpyridazin
D02.065.884.060.170 sulfadiazin 28
D02.065.884.060.180 sulfadimethoxin 3
D02.065.884.060.190 sulfadoxin 4
D02.065.884.060.200 sulfaguanidin 3
D02.065.884.060.210 sulfalen
D02.065.884.060.220 sulfamerazin 2
D02.065.884.060.230 sulfametr 4
D02.065.884.060.240 sulfamethazin 14
D02.065.884.060.250 sulfamethizol 1
D02.065.884.060.300 sulfamethoxazol 31
D02.065.884.060.325 sulfamethoxypyridazin 9
D02.065.884.060.338 sulfamonomethoxin 2
D02.065.884.060.344 sulfamoxol
D02.065.884.060.350 sulfanilamid 1
D02.065.884.060.400 sulfafenazol 3
D02.065.884.060.450 sulfapyridin 4
D02.065.884.060.500 sulfachinoxalin
D02.065.884.060.550 sulfathiazol 2
D02.065.884.060.600 sulfisomidin 1
D02.065.884.060.650 sulfisoxazol 5
D02.065.884.060.700 tamsulosin 14
D02.065.884.060.740 tolazamid
D02.065.884.060.745 tolbutamid 57
D02.065.884.060.872 tosyllysinchlormethylketon 4
D02.065.884.060.936 tosylfenylalanylchlormethylketon 4
D02.455 uhlovodíky 139
D02.455.426 cyklické uhlovodíky 24
D02.455.426.559 aromatické uhlovodíky 50
D02.455.426.559.389 benzenové deriváty 73
D02.455.426.559.389.085 benzensulfonamidy 2
D02.455.426.559.389.085.003 acetohexamid
D02.455.426.559.389.085.005 bosentan 16
D02.455.426.559.389.085.010 karbutamid 2
D02.455.426.559.389.085.020 celekoxib 13
D02.455.426.559.389.085.040 chlorpropamid 9
D02.455.426.559.389.085.050 chlorthalidon 41
D02.455.426.559.389.085.100 gliklazid 63
D02.455.426.559.389.085.150 mafenid 1
D02.455.426.559.389.085.160 sulfachlorpyridazin
D02.455.426.559.389.085.170 sulfadiazin 28
D02.455.426.559.389.085.180 sulfadimethoxin 3
D02.455.426.559.389.085.190 sulfadoxin 4
D02.455.426.559.389.085.200 sulfaguanidin 3
D02.455.426.559.389.085.210 sulfalen
D02.455.426.559.389.085.220 sulfamerazin 2
D02.455.426.559.389.085.230 sulfametr 4
D02.455.426.559.389.085.240 sulfamethazin 14
D02.455.426.559.389.085.250 sulfamethizol 1
D02.455.426.559.389.085.300 sulfamethoxazol 31
D02.455.426.559.389.085.325 sulfamethoxypyridazin 9
D02.455.426.559.389.085.338 sulfamonomethoxin 2
D02.455.426.559.389.085.344 sulfamoxol
D02.455.426.559.389.085.350 sulfanilamid 1
D02.455.426.559.389.085.400 sulfafenazol 3
D02.455.426.559.389.085.450 sulfapyridin 4
D02.455.426.559.389.085.500 sulfachinoxalin
D02.455.426.559.389.085.550 sulfathiazol 2
D02.455.426.559.389.085.600 sulfisomidin 1
D02.455.426.559.389.085.650 sulfisoxazol 5
D02.455.426.559.389.085.700 tamsulosin 14
D02.455.426.559.389.085.740 tolazamid
D02.455.426.559.389.085.745 tolbutamid 57
D02.455.426.559.389.085.872 tosyllysinchlormethylketon 4
D02.455.426.559.389.085.936 tosylfenylalanylchlormethylketon 4
D02.886 sloučeniny síry 42
D02.886.590 sulfony 122
D02.886.590.700 sulfonamidy 767
D02.886.590.700.090 benzensulfonamidy 2
D02.886.590.700.090.003 acetohexamid
D02.886.590.700.090.005 bosentan 16
D02.886.590.700.090.010 karbutamid 2
D02.886.590.700.090.020 celekoxib 13
D02.886.590.700.090.040 chlorpropamid 9
D02.886.590.700.090.050 chlorthalidon 41
D02.886.590.700.090.100 gliklazid 63
D02.886.590.700.090.150 mafenid 1
D02.886.590.700.090.160 sulfachlorpyridazin
D02.886.590.700.090.170 sulfadiazin 28
D02.886.590.700.090.180 sulfadimethoxin 3
D02.886.590.700.090.190 sulfadoxin 4
D02.886.590.700.090.200 sulfaguanidin 3
D02.886.590.700.090.210 sulfalen
D02.886.590.700.090.220 sulfamerazin 2
D02.886.590.700.090.230 sulfametr 4
D02.886.590.700.090.240 sulfamethazin 14
D02.886.590.700.090.250 sulfamethizol 1
D02.886.590.700.090.300 sulfamethoxazol 31
D02.886.590.700.090.325 sulfamethoxypyridazin 9
D02.886.590.700.090.338 sulfamonomethoxin 2
D02.886.590.700.090.344 sulfamoxol
D02.886.590.700.090.350 sulfanilamid 1
D02.886.590.700.090.400 sulfafenazol 3
D02.886.590.700.090.450 sulfapyridin 4
D02.886.590.700.090.500 sulfachinoxalin
D02.886.590.700.090.550 sulfathiazol 2
D02.886.590.700.090.600 sulfisomidin 1
D02.886.590.700.090.650 sulfisoxazol 5
D02.886.590.700.090.700 tamsulosin 14
D02.886.590.700.090.740 tolazamid
D02.886.590.700.090.745 tolbutamid 57
D02.886.590.700.090.872 tosyllysinchlormethylketon 4
D02.886.590.700.090.936 tosylfenylalanylchlormethylketon 4
D02.886.590.700.120 benzolamid
D02.886.590.700.135 benzothiadiaziny 9
D02.886.590.700.143 bosentan 16
D02.886.590.700.150 bumetanid 7
D02.886.590.700.247 celekoxib 13
D02.886.590.700.365 chlorthalidon 41
D02.886.590.700.390 klopamid 1
D02.886.590.700.400 darunavir 5
D02.886.590.700.410 dichlorfenamid
D02.886.590.700.420 ethoxzolamid
D02.886.590.700.540 indapamid 213
D02.886.590.700.545 1-(5-isochinolinsulfonyl)-2-methylpiperazin 7
D02.886.590.700.570 mafenid 1
D02.886.590.700.575 mefrusid
D02.886.590.700.600 metolazon 1
D02.886.590.700.625 probenecid 17
D02.886.590.700.650 rosuvastatin kalcium 76
D02.886.590.700.675 sildenafil citrát 24
D02.886.590.700.700 simeprevir 12
D02.886.590.700.725 sulfanilamidy 81
D02.886.590.700.730 sulfasalazin 113
D02.886.590.700.750 sumatriptan 55
D02.886.590.700.863 tamsulosin 14
D02.886.590.700.891 torasemid 1
D02.886.590.700.919 vemurafenib 67
D02.886.590.700.975 xipamid
D02.886.590.700.987 zonisamid 4
D03 heterocyklické sloučeniny 189
D03.383 heterocyklické sloučeniny monocyklické 34
D03.383.742 pyrimidiny 959
D03.383.742.060 bosentan 16
D03.383.742.120 buspiron 33
D03.383.742.148 dasatinib 74
D03.383.742.175 dipyridamol 149
D03.383.742.200 epirizol
D03.383.742.279 hexetidin 5
D03.383.742.349 imatinib mesylát 125
D03.383.742.418 minoxidil 48
D03.383.742.430 mopidamol
D03.383.742.440 morantel
D03.383.742.470 nikarbazin
D03.383.742.550 oxypurinol 1
D03.383.742.592 paliperidon palmitát 17
D03.383.742.634 pyrantel 2
D03.383.742.675 pyrimethamin 58
D03.383.742.680 pyrimidinové nukleosidy 23
D03.383.742.686 pyrimidinové nukleotidy 14
D03.383.742.698 pyrimidinony 74
D03.383.742.715 pyrithiamin
D03.383.742.755 rilpivirin 6
D03.383.742.775 rosuvastatin kalcium 76
D03.383.742.795 thiamin 134
D03.383.742.875 trapidil
D03.383.742.906 trimethoprim 64

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