Bosentan [bosentan]

topical
16
Terms

bosentan monohydrát
Stayveer

 

4-t-Butyl-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide
Bosentan Anhydrous
Bosentan Monohydrate
Ro 47-0203
Ro-47-0203
Tracleer

Persistent link   https://www.medvik.cz/link/D000077300
Definition

A sulfonamide and pyrimidine derivative that acts as a dual endothelin receptor antagonist used to manage PULMONARY HYPERTENSION and SYSTEMIC SCLEROSIS.

DUI
D000077300 MeSH Browser
CUI
M000640413
CAS
Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)(2,2'-bipyrimidin)-4-yl)-
History note
2019 (1994)
Public note
2019; BOSENTAN was indexed under SULFONAMIDES 1995-2018; and under RECEPTORS, ENDOTHELIN/antagonists 1994

Allowable subheadings

AD
administration & dosage 1
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology 2
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use 1
TO
toxicity
UR
urine

D Chemicals and Drugs
D02 Organic Chemicals 391
D02.065 Amides 260
D02.065.884 Sulfonamides 774
D02.065.884.060 Benzenesulfonamides 3
D02.065.884.060.003 Acetohexamide
D02.065.884.060.005 Bosentan 16
D02.065.884.060.010 Carbutamide 2
D02.065.884.060.020 Celecoxib 14
D02.065.884.060.040 Chlorpropamide 9
D02.065.884.060.050 Chlorthalidone 41
D02.065.884.060.100 Gliclazide 63
D02.065.884.060.150 Mafenide 1
D02.065.884.060.160 Sulfachlorpyridazine
D02.065.884.060.170 Sulfadiazine 28
D02.065.884.060.180 Sulfadimethoxine 3
D02.065.884.060.190 Sulfadoxine 4
D02.065.884.060.200 Sulfaguanidine 3
D02.065.884.060.210 Sulfalene
D02.065.884.060.220 Sulfamerazine 2
D02.065.884.060.230 Sulfameter 4
D02.065.884.060.240 Sulfamethazine 14
D02.065.884.060.250 Sulfamethizole 1
D02.065.884.060.300 Sulfamethoxazole 31
D02.065.884.060.325 Sulfamethoxypyridazine 9
D02.065.884.060.338 Sulfamonomethoxine 2
D02.065.884.060.344 Sulfamoxole
D02.065.884.060.350 Sulfanilamide 1
D02.065.884.060.400 Sulfaphenazole 3
D02.065.884.060.450 Sulfapyridine 4
D02.065.884.060.500 Sulfaquinoxaline
D02.065.884.060.550 Sulfathiazole 2
D02.065.884.060.600 Sulfisomidine 1
D02.065.884.060.650 Sulfisoxazole 5
D02.065.884.060.700 Tamsulosin 14
D02.065.884.060.740 Tolazamide
D02.065.884.060.745 Tolbutamide 57
D02.065.884.060.872 Tosyllysine Chloromethyl Ketone 4
D02.065.884.060.936 Tosylphenylalanyl Chloromethyl Ketone 4
D02.455 Hydrocarbons 139
D02.455.426 Hydrocarbons, Cyclic 24
D02.455.426.559 Hydrocarbons, Aromatic 50
D02.455.426.559.389 Benzene Derivatives 73
D02.455.426.559.389.085 Benzenesulfonamides 3
D02.455.426.559.389.085.003 Acetohexamide
D02.455.426.559.389.085.005 Bosentan 16
D02.455.426.559.389.085.010 Carbutamide 2
D02.455.426.559.389.085.020 Celecoxib 14
D02.455.426.559.389.085.040 Chlorpropamide 9
D02.455.426.559.389.085.050 Chlorthalidone 41
D02.455.426.559.389.085.100 Gliclazide 63
D02.455.426.559.389.085.150 Mafenide 1
D02.455.426.559.389.085.160 Sulfachlorpyridazine
D02.455.426.559.389.085.170 Sulfadiazine 28
D02.455.426.559.389.085.180 Sulfadimethoxine 3
D02.455.426.559.389.085.190 Sulfadoxine 4
D02.455.426.559.389.085.200 Sulfaguanidine 3
D02.455.426.559.389.085.210 Sulfalene
D02.455.426.559.389.085.220 Sulfamerazine 2
D02.455.426.559.389.085.230 Sulfameter 4
D02.455.426.559.389.085.240 Sulfamethazine 14
D02.455.426.559.389.085.250 Sulfamethizole 1
D02.455.426.559.389.085.300 Sulfamethoxazole 31
D02.455.426.559.389.085.325 Sulfamethoxypyridazine 9
D02.455.426.559.389.085.338 Sulfamonomethoxine 2
D02.455.426.559.389.085.344 Sulfamoxole
D02.455.426.559.389.085.350 Sulfanilamide 1
D02.455.426.559.389.085.400 Sulfaphenazole 3
D02.455.426.559.389.085.450 Sulfapyridine 4
D02.455.426.559.389.085.500 Sulfaquinoxaline
D02.455.426.559.389.085.550 Sulfathiazole 2
D02.455.426.559.389.085.600 Sulfisomidine 1
D02.455.426.559.389.085.650 Sulfisoxazole 5
D02.455.426.559.389.085.700 Tamsulosin 14
D02.455.426.559.389.085.740 Tolazamide
D02.455.426.559.389.085.745 Tolbutamide 57
D02.455.426.559.389.085.872 Tosyllysine Chloromethyl Ketone 4
D02.455.426.559.389.085.936 Tosylphenylalanyl Chloromethyl Ketone 4
D02.886 Sulfur Compounds 42
D02.886.590 Sulfones 123
D02.886.590.700 Sulfonamides 774
D02.886.590.700.090 Benzenesulfonamides 3
D02.886.590.700.090.003 Acetohexamide
D02.886.590.700.090.005 Bosentan 16
D02.886.590.700.090.010 Carbutamide 2
D02.886.590.700.090.020 Celecoxib 14
D02.886.590.700.090.040 Chlorpropamide 9
D02.886.590.700.090.050 Chlorthalidone 41
D02.886.590.700.090.100 Gliclazide 63
D02.886.590.700.090.150 Mafenide 1
D02.886.590.700.090.160 Sulfachlorpyridazine
D02.886.590.700.090.170 Sulfadiazine 28
D02.886.590.700.090.180 Sulfadimethoxine 3
D02.886.590.700.090.190 Sulfadoxine 4
D02.886.590.700.090.200 Sulfaguanidine 3
D02.886.590.700.090.210 Sulfalene
D02.886.590.700.090.220 Sulfamerazine 2
D02.886.590.700.090.230 Sulfameter 4
D02.886.590.700.090.240 Sulfamethazine 14
D02.886.590.700.090.250 Sulfamethizole 1
D02.886.590.700.090.300 Sulfamethoxazole 31
D02.886.590.700.090.325 Sulfamethoxypyridazine 9
D02.886.590.700.090.338 Sulfamonomethoxine 2
D02.886.590.700.090.344 Sulfamoxole
D02.886.590.700.090.350 Sulfanilamide 1
D02.886.590.700.090.400 Sulfaphenazole 3
D02.886.590.700.090.450 Sulfapyridine 4
D02.886.590.700.090.500 Sulfaquinoxaline
D02.886.590.700.090.550 Sulfathiazole 2
D02.886.590.700.090.600 Sulfisomidine 1
D02.886.590.700.090.650 Sulfisoxazole 5
D02.886.590.700.090.700 Tamsulosin 14
D02.886.590.700.090.740 Tolazamide
D02.886.590.700.090.745 Tolbutamide 57
D02.886.590.700.090.872 Tosyllysine Chloromethyl Ketone 4
D02.886.590.700.090.936 Tosylphenylalanyl Chloromethyl Ketone 4
D02.886.590.700.120 Benzolamide
D02.886.590.700.135 Benzothiadiazines 9
D02.886.590.700.143 Bosentan 16
D02.886.590.700.150 Bumetanide 7
D02.886.590.700.247 Celecoxib 14
D02.886.590.700.365 Chlorthalidone 41
D02.886.590.700.390 Clopamide 1
D02.886.590.700.400 Darunavir 5
D02.886.590.700.410 Dichlorphenamide
D02.886.590.700.420 Ethoxzolamide
D02.886.590.700.540 Indapamide 214
D02.886.590.700.545 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine 7
D02.886.590.700.570 Mafenide 1
D02.886.590.700.575 Mefruside
D02.886.590.700.600 Metolazone 1
D02.886.590.700.625 Probenecid 17
D02.886.590.700.650 Rosuvastatin Calcium 77
D02.886.590.700.675 Sildenafil Citrate 25
D02.886.590.700.700 Simeprevir 12
D02.886.590.700.725 Sulfanilamides 81
D02.886.590.700.730 Sulfasalazine 113
D02.886.590.700.750 Sumatriptan 55
D02.886.590.700.863 Tamsulosin 14
D02.886.590.700.891 Torsemide 1
D02.886.590.700.919 Vemurafenib 67
D02.886.590.700.975 Xipamide
D02.886.590.700.987 Zonisamide 4
D03 Heterocyclic Compounds 190
D03.383 Heterocyclic Compounds, 1-Ring 34
D03.383.742 Pyrimidines 982
D03.383.742.060 Bosentan 16
D03.383.742.120 Buspirone 33
D03.383.742.148 Dasatinib 76
D03.383.742.175 Dipyridamole 149
D03.383.742.200 Epirizole
D03.383.742.279 Hexetidine 5
D03.383.742.349 Imatinib Mesylate 127
D03.383.742.418 Minoxidil 49
D03.383.742.430 Mopidamol
D03.383.742.440 Morantel
D03.383.742.470 Nicarbazin
D03.383.742.550 Oxypurinol 1
D03.383.742.592 Paliperidone Palmitate 17
D03.383.742.634 Pyrantel 2
D03.383.742.675 Pyrimethamine 58
D03.383.742.680 Pyrimidine Nucleosides 23
D03.383.742.686 Pyrimidine Nucleotides 14
D03.383.742.698 Pyrimidinones 75
D03.383.742.715 Pyrithiamine
D03.383.742.755 Rilpivirine 6
D03.383.742.775 Rosuvastatin Calcium 77
D03.383.742.795 Thiamine 135
D03.383.742.875 Trapidil
D03.383.742.906 Trimethoprim 64

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