Omalizumab [omalizumab]
topical
112
- Terms
-
Xolair
-
Xolair
Persistent link
https://www.medvik.cz/link/D000069444
Definition
An anti-IgE, recombinant, humanized monoclonal antibody which specifically binds to the C epsilon3 domain of IMMUNOGLOBULIN E, the site of high-affinity IgE receptor binding. It inhibits the binding of IgE to MAST CELLS and BASOPHILS to reduce the severity of the allergic response and is used in the management of persistent allergic ASTHMA.
- DUI
- D000069444 MeSH Browser
- CUI
- M0387411
- CAS
- Immunoglobulin G, anti-(human immunoglobulin E Fc region)(human-mouse monoclonal E25 clone pSVIE26 gamma-chain), disulfide with human-mouse monoclonal E25 clone pSVIE26 kappa-chain, dimer
- History note
- 2016 (2001)
- Public note
- 2016; OMALIZUMAB was indexed under ANTIBODIES, ANTI-IDIOTYPIC and ANTIBODIES, MONOCLONAL, HUMANIZED 2011-2015; and under ANTIBODIES, MONOCLONAL 2001-2011
Allowable subheadings
- AD
- administration & dosage 33
- AE
- adverse effects 13
- AN
- analysis
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CH
- chemistry
- CL
- classification
- DE
- drug effects
- EC
- economics 5
- GE
- genetics
- HI
- history
- IM
- immunology 1
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology 28
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- TU
- therapeutic use 76
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
...
Occurrences in Medvik records
D
Chemicals and Drugs