Denosumab [denosumab]

topical
157
Terms

Prolia
Xgeva

 

AMG 162
Prolia
Xgeva

Persistent link   https://www.medvik.cz/link/D000069448
Definition

A humanized monoclonal antibody and an inhibitor of the RANK LIGAND, which regulates OSTEOCLAST differentiation and bone remodeling. It is used as a BONE DENSITY CONSERVATION AGENT in the treatment of OSTEOPOROSIS.

DUI
D000069448 MeSH Browser
CUI
M0493770
History note
2016 (2004)
Public note
2016; DENOSUMAB was indexed under ANTIBODIES, MONOCLONAL, HUMANIZED 2012-2015; and under ANTIBODIES, MONOCLONAL 2004-2012

Allowable subheadings

AD
administration & dosage 38
AE
adverse effects 35
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CH
chemistry
CL
classification
DE
drug effects
EC
economics 3
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics 5
PD
pharmacology 29
PH
physiology
PO
poisoning
RE
radiation effects
TU
therapeutic use 98
TO
toxicity 1
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 584
D12.776.124 Blood Proteins 910
D12.776.124.486 Immunoproteins 14
D12.776.124.486.485 Immunoglobulins 1 493
D12.776.124.486.485.114 Antibodies 1 816
D12.776.124.486.485.114.224 Antibodies, Monoclonal 4 693
D12.776.124.486.485.114.224.060 Antibodies, Monoclonal, Humanized 2 935
D12.776.124.486.485.114.224.060.125 Abciximab 14
D12.776.124.486.485.114.224.060.250 Adalimumab 353
D12.776.124.486.485.114.224.060.313 Alemtuzumab 125
D12.776.124.486.485.114.224.060.344 Basiliximab 2
D12.776.124.486.485.114.224.060.375 Bevacizumab 453
D12.776.124.486.485.114.224.060.438 Brentuximab Vedotin 44
D12.776.124.486.485.114.224.060.500 Certolizumab Pegol 48
D12.776.124.486.485.114.224.060.750 Cetuximab 186
D12.776.124.486.485.114.224.060.766 Daclizumab 6
D12.776.124.486.485.114.224.060.782 Denosumab 157
D12.776.124.486.485.114.224.060.790 Gemtuzumab 18
D12.776.124.486.485.114.224.060.794 Inotuzumab Ozogamicin 12
D12.776.124.486.485.114.224.060.798 Ipilimumab 267
D12.776.124.486.485.114.224.060.813 Natalizumab 158
D12.776.124.486.485.114.224.060.829 Nivolumab 459
D12.776.124.486.485.114.224.060.844 Omalizumab 114
D12.776.124.486.485.114.224.060.860 Palivizumab 13
D12.776.124.486.485.114.224.060.864 Panitumumab 62
D12.776.124.486.485.114.224.060.866 Ramucirumab 1
D12.776.124.486.485.114.224.060.868 Ranibizumab 63
D12.776.124.486.485.114.224.060.875 Trastuzumab 278
D12.776.124.486.485.114.224.060.937 Ustekinumab 124
D12.776.124.790 Serum Globulins 61
D12.776.124.790.651 Immunoglobulins 1 493
D12.776.124.790.651.114 Antibodies 1 816
D12.776.124.790.651.114.224 Antibodies, Monoclonal 4 693
D12.776.124.790.651.114.224.060 Antibodies, Monoclonal, Humanized 2 935
D12.776.124.790.651.114.224.060.125 Abciximab 14
D12.776.124.790.651.114.224.060.250 Adalimumab 353
D12.776.124.790.651.114.224.060.375 Alemtuzumab 125
D12.776.124.790.651.114.224.060.407 Basiliximab 2
D12.776.124.790.651.114.224.060.438 Bevacizumab 453
D12.776.124.790.651.114.224.060.469 Brentuximab Vedotin 44
D12.776.124.790.651.114.224.060.500 Certolizumab Pegol 48
D12.776.124.790.651.114.224.060.750 Cetuximab 186
D12.776.124.790.651.114.224.060.766 Daclizumab 6
D12.776.124.790.651.114.224.060.782 Denosumab 157
D12.776.124.790.651.114.224.060.790 Gemtuzumab 18
D12.776.124.790.651.114.224.060.794 Inotuzumab Ozogamicin 12
D12.776.124.790.651.114.224.060.798 Ipilimumab 267
D12.776.124.790.651.114.224.060.813 Natalizumab 158
D12.776.124.790.651.114.224.060.829 Nivolumab 459
D12.776.124.790.651.114.224.060.844 Omalizumab 114
D12.776.124.790.651.114.224.060.860 Palivizumab 13
D12.776.124.790.651.114.224.060.864 Panitumumab 62
D12.776.124.790.651.114.224.060.866 Ramucirumab 1
D12.776.124.790.651.114.224.060.868 Ranibizumab 63
D12.776.124.790.651.114.224.060.875 Trastuzumab 278
D12.776.124.790.651.114.224.060.937 Ustekinumab 124
D12.776.377 Globulins 68
D12.776.377.715 Serum Globulins 61
D12.776.377.715.548 Immunoglobulins 1 493
D12.776.377.715.548.114 Antibodies 1 816
D12.776.377.715.548.114.224 Antibodies, Monoclonal 4 693
D12.776.377.715.548.114.224.200 Antibodies, Monoclonal, Humanized 2 935
D12.776.377.715.548.114.224.200.125 Abciximab 14
D12.776.377.715.548.114.224.200.250 Adalimumab 353
D12.776.377.715.548.114.224.200.375 Alemtuzumab 125
D12.776.377.715.548.114.224.200.407 Basiliximab 2
D12.776.377.715.548.114.224.200.438 Bevacizumab 453
D12.776.377.715.548.114.224.200.469 Brentuximab Vedotin 44
D12.776.377.715.548.114.224.200.500 Certolizumab Pegol 48
D12.776.377.715.548.114.224.200.750 Cetuximab 186
D12.776.377.715.548.114.224.200.766 Daclizumab 6
D12.776.377.715.548.114.224.200.782 Denosumab 157
D12.776.377.715.548.114.224.200.790 Gemtuzumab 18
D12.776.377.715.548.114.224.200.794 Inotuzumab Ozogamicin 12
D12.776.377.715.548.114.224.200.798 Ipilimumab 267
D12.776.377.715.548.114.224.200.813 Natalizumab 158
D12.776.377.715.548.114.224.200.829 Nivolumab 459
D12.776.377.715.548.114.224.200.844 Omalizumab 114
D12.776.377.715.548.114.224.200.860 Palivizumab 13
D12.776.377.715.548.114.224.200.864 Panitumumab 62
D12.776.377.715.548.114.224.200.866 Ramucirumab 1
D12.776.377.715.548.114.224.200.868 Ranibizumab 63
D12.776.377.715.548.114.224.200.875 Trastuzumab 278
D12.776.377.715.548.114.224.200.937 Ustekinumab 124

QL1206 Chemical MeSH Browser

Add