Nogo Proteins [Nogo proteiny]
- Terms
-
Nogo-66 protein
Nogo-A protein
Nogo-B protein
Nogo-C protein
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Neurite Growth Inhibitor 35-350
NI-220 Protein
NI-250 Protein
NI-35 Protein
NI-35-250
Nogo Protein
Nogo-66 Protein
Nogo-A Protein
Nogo-B Protein
Nogo-C Protein
Reticulon 4-B Protein
Reticulon-4 Protein
Myelin proteins that are expressed as three isoforms: Nogo-A, Nogo-B, and Nogo-C. These share a C-terminal reticulon homology domain (RHD), consisting of two hydrophobic membrane domains flanking a 66 amino acid (Nogo-66) hydrophilic region. A long transmembrane region allows conformations that either span the entire membrane or fold into a hairpin conformation. Nogo inhibits NEURITE outgrowth and modulates wiring and the restriction of SYNAPTIC PLASTICITY in the adult central nervous system. It also regulates neurite fasciculation, branching, and extension in the developing nervous system.
- DUI
- D000070798 MeSH Browser
- CUI
- M0356759
- History note
- 2017 (2000)
- Public note
- 2017; NOGO PROTEIN was indexed under MYELIN PROTEINS 2000-2016
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