Nogo proteiny [Nogo Proteins]

tematický
2
Termíny

Nogo-66 protein
Nogo-A protein
Nogo-B protein
Nogo-C protein

 

Neurite Growth Inhibitor 35-350
NI-220 Protein
NI-250 Protein
NI-35 Protein
NI-35-250
Nogo Protein
Nogo-66 Protein
Nogo-A Protein
Nogo-B Protein
Nogo-C Protein
Reticulon 4-B Protein
Reticulon-4 Protein

Perzistentní odkaz   https://www.medvik.cz/link/D000070798
Definice

Myelin proteins that are expressed as three isoforms: Nogo-A, Nogo-B, and Nogo-C. These share a C-terminal reticulon homology domain (RHD), consisting of two hydrophobic membrane domains flanking a 66 amino acid (Nogo-66) hydrophilic region. A long transmembrane region allows conformations that either span the entire membrane or fold into a hairpin conformation. Nogo inhibits NEURITE outgrowth and modulates wiring and the restriction of SYNAPTIC PLASTICITY in the adult central nervous system. It also regulates neurite fasciculation, branching, and extension in the developing nervous system.

DUI
D000070798 MeSH Prohlížeč
CUI
M0356759
Historická pozn.
2017 (2000)
Veřejná pozn.
2017; NOGO PROTEIN was indexed under MYELIN PROTEINS 2000-2016