Tensins [tensiny]
- Terms
-
tensin
-
Tensin
A family of multidomain microfilament proteins that bind ACTIN FILAMENTS and INTEGRINS at FOCAL ADHESIONS. They generally consist of an N-terminal domain with homology to PHOSPHOTYROSINE PHOSPHATASE, a C2 DOMAIN; unique central regions rich in PROLINE; ALANINE; GLYCINE; and SERINE; an SH2 DOMAIN; and a C-terminal phosphotyrosine-binding region. They are involved in CELL MIGRATION; CELL ADHESION; SIGNAL TRANSDUCTION; and reorganization of the CYTOSKELETON.
- DUI
- D000070876 MeSH Browser
- CUI
- M0201606
- History note
- 2017 (1992)
- Public note
- 2017; TENSINS was indexed under MICROFILAMENT PROTEINS (1992-2016)
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics 1
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
TNS1 protein, human Chemical MeSH Browser
TNS2 protein, human Chemical MeSH Browser
TNS3 protein, human Chemical MeSH Browser
TNS4 protein, human Chemical MeSH Browser
Tns1 protein, mouse Chemical MeSH Browser
Tns1 protein, rat Chemical MeSH Browser
Tns2 protein, mouse Chemical MeSH Browser
Tns2 protein, rat Chemical MeSH Browser
Tns3 protein, mouse Chemical MeSH Browser
Tns3 protein, rat Chemical MeSH Browser
Tns4 protein, mouse Chemical MeSH Browser
Tns4 protein, rat Chemical MeSH Browser
tns-1 protein, C elegans Chemical MeSH Browser