MutL Protein Homolog 1 [MutL homolog 1]
- Terms
-
MLH1
protein COCA2
protein MLH1
-
COCA2 Protein
Colon Cancer, Nonpolyposis Type 2 Protein
MLH1 Protein
MutL Homolog 1
Eukaryotic homolog of the bacterial MutL DNA MISMATCH REPAIR protein. It heterodimerizes with MISMATCH REPAIR ENDONUCLEASE PMS2 to form MutL alpha, which is recruited to DNA mismatch sites by the MUTS DNA MISMATCH-BINDING PROTEIN. Mutations in the human MLH1 gene are associated with COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS.
- DUI
- D000070957 MeSH Browser
- CUI
- M000612746
- Previous indexing
- Adaptor Proteins, Signal Transducing (1994-2016); Nuclear Proteins (1995-2016)
- History note
- 2017
- Public note
- 2017
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AN
- analysis 1
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency 1
- DE
- drug effects
- EC
- economics
- GE
- genetics 11
- HI
- history
- IM
- immunology 1
- IP
- isolation & purification
- ME
- metabolism 3
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology 1
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
MLH1 protein, Arabidopsis Chemical MeSH Browser
MLH1 protein, S cerevisiae Chemical MeSH Browser
MLH1 protein, human Chemical MeSH Browser
Mlh1 protein, mouse Chemical MeSH Browser
Mlh1 protein, rat Chemical MeSH Browser
Mlh1 protein, zebrafish Chemical MeSH Browser