Mismatch Repair Endonuclease PMS2 [mismatch repair endonukleáza PMS2]
topical
8
- Terms
-
endonukleáza PMS2 s funkcí mismatch repair
endonukleáza PMS2 s funkcí opravy DNA
endonukleáza PMS2 se schopností opravy DNA
protein PMS-2
protein PMS2
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PMS-2 Protein
PMS1 Homolog 2, Mismatch Repair Protein
PMS2 Protein
Postmeiotic Segregation Increased-S. cerevisiae-2
Persistent link
https://www.medvik.cz/link/D000070976
Definition
A MutL protein and component of the DNA MISMATCH REPAIR system. Its ENDONUCLEASE activity introduces SINGLE-STRAND DNA BREAKS which create entry points for EXO1 exonuclease to remove the strand containing the mismatch. It may also function in DNA DAMAGE signaling.
- DUI
- D000070976 MeSH Browser
- CUI
- M000612774
- RN
- EC 3.6.1.3
- Previous indexing
- Adenosine Triphosphatases (2001-2016); DNA Repair Enzymes (2001-2016)
- History note
- 2017
- Public note
- 2017
Allowable subheadings
- AD
- administration & dosage 0
- AE
- adverse effects 0
- AN
- analysis 0
- AI
- antagonists & inhibitors 0
- BI
- biosynthesis 0
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- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 0
- CL
- classification 0
- DF
- deficiency 0
- DE
- drug effects 0
- EC
- economics 0
- GE
- genetics 6
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 0
- ME
- metabolism 3
- PK
- pharmacokinetics 0
- PD
- pharmacology 0
- PH
- physiology 0
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 0
- TO
- toxicity 0
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- UR
- urine 0
...
Occurrences in Medvik records
D
Chemicals and Drugs
D08.811.074.766
MutL Proteins
D08.811.277.040.025.215
MutL Proteins
D08.811.277.352.335.350.275
Deoxyribonuclease IV (Phage T4-Induced)
D12.776.260.540
MutL Proteins