protein NLRP3 [NLR Family, Pyrin Domain-Containing 3 Protein]

tematický
19
Termíny

NLRP3 protein

 

Cold Autoinflammatory Syndrome 1 Protein
NACHT, LRR and PYD Domains-Containing Protein 3
NLRP3 Protein

Perzistentní odkaz   https://www.medvik.cz/link/D000071199
Definice

An NLR protein that contains an N-terminal PYRIN DOMAIN and ATP-binding site and 9 C-terminal LEUCINE-rich repeats; it is expressed primarily by MACROPHAGES. It is a core component of the INFLAMMASOME and directs its assembly in response to pathogen infection and damage-associated stimuli. Mutations in the NLRP3 gene are associated with FAMILIAL COLD AUTOINFLAMMATORY SYNDROME.

DUI
D000071199 MeSH Prohlížeč
CUI
M000613582
Předchozí užití
Carrier Proteins (2002-2016)
Historická pozn.
2017
Veřejná pozn.
2017