Lumican [lumican]
- Terms
-
proteoglykan lumican
-
Lumican Proteoglycan
A small leucine-rich proteoglycan that contains 10 tandem leucine repeats and four N-linked sites within the leucine repeat region that may be substituted with KERATAN SULFATE. These properties and its horseshoe shape allow it to mediate interactions among COLLAGEN molecules within fibrils. It is expressed in most mesenchymal tissues as well as the CORNEA, where it functions to maintain transparency.
- DUI
- D000071234 MeSH Browser
- CUI
- M0087653
- History note
- 2017 (1978)
- Public note
- 2017; LUMICAN was indexed under KERATAN SULFATE and CHONDROITIN SULFATE PROTEOGLYCANS 1981-2016, and under KERATAN SULFATE/ANALOGS 1978-1981
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
LUM protein, human Chemical MeSH Browser
Lum protein, mouse Chemical MeSH Browser
Lum protein, rat Chemical MeSH Browser