Macromolecular organic compounds that contain carbon, hydrogen, oxygen, nitrogen, and usually, sulfur. These macromolecules (proteins) form an intricate meshwork in which cells are embedded to construct tissues. Variations in the relative types of macromolecules and their organization determine the type of extracellular matrix, each adapted to the functional requirements of the tissue. The two main classes of macromolecules that form the extracellular matrix are: glycosaminoglycans, usually linked to proteins (proteoglycans), and fibrous proteins (e.g., COLLAGEN; ELASTIN; FIBRONECTINS; and LAMININ).

Anotace

/drug eff /ultrastruct permitted

DUI

D016326 MeSH Prohlížeč

CUI

M0024954

Předchozí užití

Extracellular Matrix (1984-1990)

Historická pozn.

91

Veřejná pozn.

91