Keratins [keratiny]
- Terms
-
alfa-keratin
cytokeratin
keratin
proteiny asociované s keratiny
-
alpha-Keratin
Cytokeratin
Keratin
Keratin Associated Protein
Keratin-Associated Proteins
A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.
- DUI
- D007633 MeSH Browser
- CUI
- M0011957
- History note
- 2007(1966)
- Public note
- 2007; see KERATIN 1966-2006; KERATIN-ASSOCIATED PROTEINS was indexed under KERATIN 2000-2006, & under PROTEINS 1993-1999
Allowable subheadings
- AD
- administration & dosage 1
- AE
- adverse effects 1
- AG
- agonists
- AN
- analysis 43
- AI
- antagonists & inhibitors
- BI
- biosynthesis 6
- BL
- blood 11
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 12
- CL
- classification 4
- DE
- drug effects 1
- EC
- economics
- GE
- genetics 17
- HI
- history
- IM
- immunology 16
- IP
- isolation & purification 6
- ME
- metabolism 53
- PK
- pharmacokinetics
- PD
- pharmacology 2
- PH
- physiology 3
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 3
- TO
- toxicity
- UL
- ultrastructure 2
- UR
- urine 8
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