DEAD box protein 58 [DEAD Box Protein 58]

tematický
5
Termíny

RIG-I-like receptor

 

DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58
Probable ATP-Dependent RNA Helicase DDX58
RIG-I-like Receptor 1

Perzistentní odkaz   https://www.medvik.cz/link/D000071457
Definice

A DEAD-box RNA helicase that contains an N-terminal DEATH-LIKE DOMAIN, AAA+ ATPase domain, and C-terminal RNA HELICASE activity. It functions as an innate immune receptor through its recognition of viral nucleic acids. It also induces the expression of INTERFERON TYPE I and proinflammatory CYTOKINES. Its ligands include: 5'-triphosphorylated SINGLE-STRANDED RNA, DOUBLE-STRANDED RNA (dsRNA), and short dsRNA (less than 1 kb in length).

DUI
D000071457 MeSH Prohlížeč
CUI
M000614788
RN
EC 3.6.4.13
Předchozí užití
DEAD-box RNA Helicases (2006-2016)
Historická pozn.
2017
Veřejná pozn.
2017