DEAD Box Protein 58 [DEAD box protein 58]
- Terms
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RIG-I-like receptor
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DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58
Probable ATP-Dependent RNA Helicase DDX58
RIG-I-like Receptor 1
A DEAD-box RNA helicase that contains an N-terminal DEATH-LIKE DOMAIN, AAA+ ATPase domain, and C-terminal RNA HELICASE activity. It functions as an innate immune receptor through its recognition of viral nucleic acids. It also induces the expression of INTERFERON TYPE I and proinflammatory CYTOKINES. Its ligands include: 5'-triphosphorylated SINGLE-STRANDED RNA, DOUBLE-STRANDED RNA (dsRNA), and short dsRNA (less than 1 kb in length).
- DUI
- D000071457 MeSH Browser
- CUI
- M000614788
- Previous indexing
- DEAD-box RNA Helicases (2006-2016)
- History note
- 2017
- Public note
- 2017
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 1
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics 3
- HI
- history
- IM
- immunology 2
- IP
- isolation & purification
- ME
- metabolism 2
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
Ddx58 protein, mouse Chemical MeSH Browser
Ddx58 protein, rat Chemical MeSH Browser
RIGI protein, human Chemical MeSH Browser