Death Domain [doména smrti]

topical
Terms

death doména
death domény
domény smrti

 

Death Domains

Definition

A conserved protein interaction domain of the death domain superfamily that is structurally similar to the DEATH EFFECTOR DOMAIN and CASPASE RECRUITMENT DOMAIN. Death domains bind each other to form oligomers and occur on DEATH DOMAIN RECEPTORS, where they are required for APOPTOSIS signaling and non-apoptotic functions.

DUI
D000071459 MeSH Browser
CUI
M000614793
Previous indexing
Amino Acid Sequence (1995-2016); Receptors, Death Domain (2007-2016); Receptors, Tumor Necrosis Factor (1995-2016)
History note
2017
Public note
2017