Caspase Activation and Recruitment Domain [kaspasová aktivační doména]

topical
Terms

CARD doména
doména CARD
kaspázová aktivační doména

 

CARD Domain
CARD Domains
Caspase Activation and Recruitment Domains
Caspase Recruitment Domain
Caspase Recruitment Domains

Definition

A homotypic protein interaction module of the death domain superfamily. It is composed of a bundle of six alpha-helices that is related in sequence and structure to the DEATH DOMAIN and DEATH EFFECTOR DOMAIN. The Caspase Activation and Recruitment Domain (CARD domain) typically associates with other CARD-containing proteins, forming either dimers or trimers. CARD domains may occur in isolation, or in combination with other domains in CARD signaling adaptor proteins and initiator CASPASES that function in APOPTOSIS.

DUI
D000071476 MeSH Browser
CUI
M000614836
Previous indexing
Apoptosis Regulatory Proteins (2006-2016); Amino Acid Sequence (1997-2016); CARD Signaling Adaptor Proteins (2006-2016)
History note
2017
Public note
2017