Transcription Factor 4 [transkripční faktor 4]
- Terms
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protein TCF-4
transkripční faktor TCF-4
transkripční faktor TCF4
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TCF-4 Protein
TCF-4 Transcription Factor
TCF4 Transcription Factor
A basic helix-loop-helix leucine zipper transcription factor that functions in neuronal CELL DIFFERENTIATION. It dimerizes with other bHLH transcription factors and activates transcription through binding to E-BOX ELEMENTS containing 5'-ACANNTGT-3' or 5'-CCANNTGG-3' sequences. Mutations in the TCF-4 gene are associated with Pitt-Hopkins Syndrome, a severe developmental disorder.
- DUI
- D000073940 MeSH Browser
- CUI
- M000625038
- Previous indexing
- Transcription Factors (2008-2017); Basic Helix-Loop-Helix Leucine Zipper Transcription Factors (2010-2017)
- History note
- 2018
- Public note
- 2018
Allowable subheadings
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- administration & dosage
- AE
- adverse effects
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- agonists
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- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
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- chemical synthesis
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- chemistry
- CL
- classification
- DF
- deficiency
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- economics
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- genetics 7
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- history
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- immunology
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- isolation & purification
- ME
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- physiology
- PO
- poisoning
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- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
TCF4 protein, human Chemical MeSH Browser
Tcf4 protein, mouse Chemical MeSH Browser
Tcf4 protein, rat Chemical MeSH Browser
Tcf4 protein, zebrafish Chemical MeSH Browser