Aldo-Keto Reductases [aldo-keto reduktasy]

topical
3
Terms

aldo-keto reduktasa
aldo-keto reduktáza
aldo-keto reduktázy
nadrodina aldo-ketoreduktáz

 

Aldo-Keto Reductase
Aldo-Keto Reductase Family
Aldo-Keto Reductase Superfamily

Persistent link   https://www.medvik.cz/link/D000074408
Definition

A family of NADPH-dependent oxidoreductases that reduce carbonyl substrates including sugar-aldehydes, KETOSTEROIDS; keto-prostaglandins, and QUINONES. They are monomers of approximately 37 KDa and are characterized by a parallel beta-8 (BETA SHEET)-alpha 8 (ALPHA HELICES)-barrel structure that contains the NADP binding site. This conformation favors aromatic and apolar substrates.

DUI
D000074408 MeSH Browser
CUI
M000626517
Previous indexing
Aldehyde Reductase (1976-2017)
History note
2018
Public note
2018

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors 2
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry 1
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics 1
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism 3
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D08 Enzymes and Coenzymes 7
D08.811 Enzymes 1 551
D08.811.682 Oxidoreductases 446
D08.811.682.047 Alcohol Oxidoreductases 98
D08.811.682.047.150 Carbohydrate Dehydrogenases 20
D08.811.682.047.150.700 Sugar Alcohol Dehydrogenases 3
D08.811.682.047.150.700.156 Aldo-Keto Reductases 3
D08.811.682.047.150.700.156.500 Aldehyde Reductase 28
D08.811.682.047.150.700.156.625 Aldo-Keto Reductase Family 1 member B10
D08.811.682.047.150.700.156.750 Aldo-Keto Reductase Family 1 Member C2
D08.811.682.047.150.700.156.875 Aldo-Keto Reductase Family 1 Member C3 5
D08.811.682.047.150.700.156.937 20-alpha-Hydroxysteroid Dehydrogenase
D08.811.682.047.150.700.237 D-Xylulose Reductase
D08.811.682.047.150.700.400 Glycerolphosphate Dehydrogenase 41
D08.811.682.047.150.700.437 L-Gulonolactone Oxidase
D08.811.682.047.150.700.475 L-Iditol 2-Dehydrogenase 7
D08.811.682.047.150.700.649 Mannitol Dehydrogenases 1
D08.811.682.047.820 NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases
D08.811.682.047.820.100 11-beta-Hydroxysteroid Dehydrogenases 16
D08.811.682.047.820.125 20-Hydroxysteroid Dehydrogenases 7
D08.811.682.047.820.150 3-Hydroxyacyl CoA Dehydrogenases 15
D08.811.682.047.820.186 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific) 2
D08.811.682.047.820.193 3-Isopropylmalate Dehydrogenase
D08.811.682.047.820.196 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase
D08.811.682.047.820.200 Acetoin Dehydrogenase
D08.811.682.047.820.250 Alcohol Dehydrogenase 55
D08.811.682.047.820.284 Aldo-Keto Reductases 3
D08.811.682.047.820.284.500 Aldehyde Reductase 28
D08.811.682.047.820.284.750 20-alpha-Hydroxysteroid Dehydrogenase
D08.811.682.047.820.284.813 Aldo-Keto Reductase Family 1 member B10
D08.811.682.047.820.284.875 Aldo-Keto Reductase Family 1 Member C2
D08.811.682.047.820.284.937 Aldo-Keto Reductase Family 1 Member C3 5
D08.811.682.047.820.289 Carbonyl Reductase (NADPH) 2
D08.811.682.047.820.293 Glycerol-3-Phosphate Dehydrogenase (NAD+) 1
D08.811.682.047.820.300 Homoserine Dehydrogenase 1
D08.811.682.047.820.350 Hydroxybutyrate Dehydrogenase 5
D08.811.682.047.820.375 Hydroxyprostaglandin Dehydrogenases 10
D08.811.682.047.820.400 Hydroxypyruvate Reductase
D08.811.682.047.820.450 IMP Dehydrogenase 2
D08.811.682.047.820.475 Isocitrate Dehydrogenase 61
D08.811.682.047.820.487 Ketol-Acid Reductoisomerase 1
D08.811.682.047.820.493 L-Lactate Dehydrogenase 243
D08.811.682.047.820.496 Malate Dehydrogenase 88
D08.811.682.047.820.498 Malate Dehydrogenase (NADP+) 1
D08.811.682.047.820.500 Progesterone Reductase 2
D08.811.682.047.820.800 D-Xylulose Reductase
D08.811.682.047.820.900 Short Chain Dehydrogenase-Reductases 2

AKR1B10 protein, human Chemical MeSH Browser

AKR1C19 protein, mouse Chemical MeSH Browser

AKR7A5 protein, mouse Chemical MeSH Browser

Akr1b10 protein, mouse Chemical MeSH Browser

Akr1b3 protein, mouse Chemical MeSH Browser

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