Aldo-Keto Reductase Family 1 Member C2 [protein AKR1C2]
topical
- Terms
-
dihydrodioldehydrogenasa 2
dihydrodioldehydrogenáza 2
-
AKR1C2 Protein
Dihydrodiol Dehydrogenase 2
Dihydrodiol Dehydrogenase-Bile Acid Binding Protein
Persistent link
https://www.medvik.cz/link/D000074422
Definition
Aldo-keto reductase that functions with 5-alpha and 5-beta-steroid reductases to convert steroid hormones into the 3-alpha or 5-alpha and 3-alpha or 5-beta-tetrahydrosteroid, including 5-ALPHA-DIHYDROTESTOSTERONE to ANDROSTANE-3,17-DIOL. It also binds to BILE ACIDS. Mutations in the AKR1C2 gene are associated with Type 8 DISORDER OF SEX DEVELOPMENT, 46,XY (SRXY8).
- DUI
- D000074422 MeSH Browser
- CUI
- M000626529
- Previous indexing
- Hydroxysteroid Dehydrogenases (2001-2017)
- History note
- 2018
- Public note
- 2018
Allowable subheadings
- AD
- administration & dosage 0
- AE
- adverse effects 0
- AN
- analysis 0
- AI
- antagonists & inhibitors 0
- BI
- biosynthesis 0
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 0
- CL
- classification 0
- DF
- deficiency 0
- DE
- drug effects 0
- EC
- economics 0
- GE
- genetics 0
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 0
- ME
- metabolism 0
- PK
- pharmacokinetics 0
- PD
- pharmacology 0
- PH
- physiology 0
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 0
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0
...
Occurrences in Medvik records
D
Chemicals and Drugs
D08.811.682.047.150.700.156.625
Aldo-Keto Reductase Family 1 member B10
D08.811.682.047.150.700.156.750
Aldo-Keto Reductase Family 1 Member C2
D08.811.682.047.150.700.156.937
20-alpha-Hydroxysteroid Dehydrogenase
D08.811.682.047.820
NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases
D08.811.682.047.820.284.750
20-alpha-Hydroxysteroid Dehydrogenase
D08.811.682.047.820.284.813
Aldo-Keto Reductase Family 1 member B10
D08.811.682.047.820.284.875
Aldo-Keto Reductase Family 1 Member C2