Aldo-Keto Reductase Family 1 Member C2 [protein AKR1C2]
topical
- Terms
-
dihydrodioldehydrogenasa 2
dihydrodioldehydrogenáza 2
-
AKR1C2 Protein
Dihydrodiol Dehydrogenase 2
Dihydrodiol Dehydrogenase-Bile Acid Binding Protein
Persistent link
https://www.medvik.cz/link/D000074422
Definition
Aldo-keto reductase that functions with 5-alpha and 5-beta-steroid reductases to convert steroid hormones into the 3-alpha or 5-alpha and 3-alpha or 5-beta-tetrahydrosteroid, including 5-ALPHA-DIHYDROTESTOSTERONE to ANDROSTANE-3,17-DIOL. It also binds to BILE ACIDS. Mutations in the AKR1C2 gene are associated with Type 8 DISORDER OF SEX DEVELOPMENT, 46,XY (SRXY8).
- DUI
- D000074422 MeSH Browser
- CUI
- M000626529
- Previous indexing
- Hydroxysteroid Dehydrogenases (2001-2017)
- History note
- 2018
- Public note
- 2018
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
...
Occurrences in Medvik records
D
Chemicals and Drugs
D08.811.682.047.150.700.156.625
Aldo-Keto Reductase Family 1 member B10
D08.811.682.047.150.700.156.750
Aldo-Keto Reductase Family 1 Member C2
D08.811.682.047.150.700.156.937
20-alpha-Hydroxysteroid Dehydrogenase
D08.811.682.047.820
NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases
D08.811.682.047.820.284.750
20-alpha-Hydroxysteroid Dehydrogenase
D08.811.682.047.820.284.813
Aldo-Keto Reductase Family 1 member B10
D08.811.682.047.820.284.875
Aldo-Keto Reductase Family 1 Member C2